Accepting PhD Students

PhD projects

Cancer Genomics, Single Cell Biology, Genomics, Bioinformatics, Multi 'Omics, Bioconductor, Digital Pathology, Real world evidence, AI and data analytics,

1996 …2024

Research activity per year

Personal profile

Research Interests

Cancer Computational Genomics and; Digital Health Director of the Limerick Digital Cancer Center Lead the all-island eHealth-Hub for Cancer Member, All-Ireland Cancer Institute Steering Group Open Science: Bioconductor, ELIXIR, OHDSI
  • Single Cell Genomics methods for the Human Cell Atlas Program
  • Spatial Biology Methods development for the National Spatial Profiling Platform
  • Cancer genomics, clinical cancer research, translational oncology
  • Latent Space and Matrix Factorisation and Cancer Genomics algorithm development
  • Immune-Oncology, Tumor Microenvironment
  • European 1+ Million Genomes Program GDI
  • Real world evidence
Specialties: Bioconductor, R, bioinformatics, genomics, multivariate analysis, multi-omics, biostatistician, transcriptomics, proteomics, epigenomics, computational biology, mathematical oncology, tumor microenvironment, tumor immunology, neuro-immunology, kidney cancer, breast cancer, ovarian cancer, electronic health records, data harmonisation, genomics, real world data, real world evidence, data standards, open science, FAIR data

Biography

Aedín Culhane is Director of the Limerick Digital Cancer Research Centre and is Professor of Biomedical Sciences (Cancer Genomics) in the UL School of Medicine. She is a computational oncologist with expertise in multi-omics data integration, statistical genomics, clinical bioinformatics and genomics in oncology.  She has over 20 years experience in cancer genomics, of which over 15 years were in the Dana-Farber Cancer Institute and Harvard TH Chan School of Public Health in Boston, USA.
 
Her recent research focuses on algorithm development and integrative data of single cell molecular data in cancer to identify molecules that regulate and can be targeted during tumour development, progression, drug response and resistance.  She is a leader in the Bioconductor (www.bioconductor.org) community, a global open source, open development software in R for genomics and an advocate for open source science.  She is PI of the all-island eHealth- Hub for Cancer funded under the HEA North-South program in partnership with Prof Mark Lawler, Queens University Belfast.  She is a member of the Ireland 1+ million genome program and is a PI in the Genomic Data Infrastructure that will be an important step toward realising 1+MG. 

Google Scholar: https://scholar.google.com/citations user=O8OszPcAAAAJ LinkedIn Profile https://www.linkedin.com/in/aedinculhane/ ORC ID https://orcid.org/my-orcid orcid=0000-0002-1395-9734 eHealth Hub for Cancer https://ehealth4cancer.org/ 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 10 - Reduced Inequalities

Related documents

Education/Academic qualification

PhD, Cloning and Characterisation of Interleukin-18 in rat brain, University of Manchester

External positions

Lead, eHealth-Hub For Cancer

20222027

Senior Research Scientist, Dana-Farber Cancer Institute

20172021

Senior Research Scientist, Harvard T.H. Chan School of Public Health

20172021

Research Scientist, Dana-Farber Cancer Institute

20112017

Research Scientist, Harvard T.H. Chan School of Public Health

20112017

Instructor (Adjunct), Brandeis University

20082010

Research Associate, Dana-Farber Cancer Institute

20052011

Research Associate, Harvard University

20052011

Postdoctoral Fellow, University College Dublin

20032005

Postdoctoral Researcher, University College Cork

20012003

Computational Biology Support and Training Officer, Biotechnology and Biological Sciences Research Council

19992001

Keywords

  • RC0254 Neoplasms. Tumors. Oncology (including Cancer)
  • Clinical Informatics
  • QA76 Computer software
  • Bioinformatics
  • Computational Biology
  • AI
  • ML
  • QR180 Immunology
  • Tumor Microenviroment
  • QH426 Genetics
  • Genomics
  • Multi 'omics
  • Epidemiology
  • QH301 Biology
  • HA Statistics
  • Biostatistics
  • Data Science
  • Data Analytics

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