Personal profile
Research Interests
- The microenvironmental regulation of therapeutic resistance in breast cancer
- The interactions between cancer treatment and the blood brain barrier for the treatment of brain metastasis.
Teaching Interests
Biography
Education/Academic qualification
PhD, Microenvironmental regulation of breast cancer progression, University of Limer-ick
Award Date: 31 Aug 2020
Bachelor, Galway - BSc (Hons), National University of Ireland
Award Date: 1 Jan 2016
External positions
Post-doctoral Researcher, Dublin City University
1 Dec 2020 → …
Keywords
- QM Human anatomy
- RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Collagen-I influences the post-translational regulation, binding partners and role of Annexin A2 in breast cancer progression
Mahdi, A. F., Nolan, J., O’Connor, R., Lowery, A. J., Allardyce, J. M., Kiely, P. A. & McGourty, K., 2023, In: Frontiers in Oncology. 13, 1270436.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of ABT-751, a novel anti-mitotic agent able to overcome multi-drug resistance, in melanoma cells
Mahgoub, T. M., Jordan, E. J., Mahdi, A. F., Oettl, V., Huefner, S., O’Donovan, N., Crown, J. & Collins, D. M., May 2024, In: Cancer Chemotherapy and Pharmacology. 93, 5, p. 427-437 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Pre-Clinical Rationale for Amcenestrant Combinations in HER2+/ER+ Breast Cancer
Mahdi, A. F., Ashfield, N., Crown, J. & Collins, D. M., Jan 2025, In: International Journal of Molecular Sciences. 26, 2, 460.Research output: Contribution to journal › Article › peer-review
Open Access -
3D in vitro blood-brain barrier models: recent advances and their role in brain disease research and therapy
O'Halloran, L., Akinsete, O., Kogan, A. L., Wrona, M. & Mahdi, A. F., 2025, In: Frontiers in Pharmacology. 16, p. 1637602 1637602.Research output: Contribution to journal › Review article › peer-review
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Expression of annexin A2 promotes cancer progression in estrogen receptor negative breast cancers
Mahdi, A. F., Malacrida, B., Nolan, J., McCumiskey, M. E., Merrigan, A. B., Lal, A., Tormey, S., Lowery, A. J., McGourty, K. & Kiely, P. A., Jul 2020, In: Cells. 9, 7, p. 1-24 24 p., 1582.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
- 1 Membership of council
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Irish Association for Cancer Research (IACR) (External organisation)
Mahdi, A. (Member)
2024Activity: Membership › Membership of council
Press/Media
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Unlocking the potential of oral SERDs in HER2+/ER+ breast cancer
18/08/25
1 Media contribution
Press/Media
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