1998 …2025

Research activity per year

Personal profile

Research Interests

                                              My research is focused on better understanding the epidemiology, risk, clinical outcomes and treatment strategies for Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI).  We are particularly interested in understanding the relationship between AKI, CKD and major clinical outcomes as well as preventive strategies using large national and international data. Using data from the National Health and Examination Surveys (NHANES) and the US Renal Data System (USRDS), we have described the burden and clinical outcomes of several cardiovascular diseases in this vulnerable population. Our group has also advanced our understanding of treatment outcomes in dialysis and optimal dialysis strategies. Specific themes include, cardiovascular diseases and their treatment, mineral bone disease, dialysis strategies, medication prescribing, adherence to clinical guidelines, and gout and hyperuricaemia. Our team at the Graduate Entry Medical School (GEMS) have been awarded two (3-year) HRB grants to study the epidemiology of Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) in the Irish Health System. These studies will also provide a framework for the development of national surveillance systems that can be successfully used to track the burden, clinical outcomes and cost of kidney disease care in the health system.  In support of this initiative, we also work with the HSE in the deployment of national IT system in nephrology which will be used to bolster clinical and epidemiological research in Ireland. Emerging areas of interest include Big Data in health and Connected Health in order to improve health system performance and overall patient outcomes.                        

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education
  • SDG 10 - Reduced Inequalities

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Collaborations and top research areas from the last five years

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  • Combination Treatment with Verinurad and Allopurinol in CKD: A Randomized Placebo and Active Controlled Trial

    Heerspink, H. J. L., Stack, A. G., Terkeltaub, R., Jongs, N., Inker, L. A., Bjursell, M., Maklad, N., Perl, S., Eklund, O., Rikte, T., Sjöström, C. D., Perkovic, V., Chmelickova, H., Lukac, M., Bucek, P., Drasnar, T., Dussol, B., Guerrot, D., Legrand, E. & Boffa, J. J. & 174 others, Halimi, J. M., Zaoui, P., Letoha, A., Hajdu, C., Pall, D., Peterfai, E., Csécsei, G., Bezzegh, K., Deak, L., Konyves, L., Zsom, M., Danos, P., Vangel, S., Vasas, S., Oroszlan, T., Zilahi, Z., Leiba, A., Grossman, A., Leibowitz, A., Itzhak, B., Daoud, D., Farber, E., Adawi, F., Nakhoul, F. M., Chernin, G., Kenis, I., Wainstein, J., Zeller, L., Elias, M., Atar, S., Frajewicki, V., Yagil, Y., Armaly, Z. A., Esposito, C., Viazzi, F., Gambaro, G., Piatti, P., Bonadonna, R. C., Arias Delgadillo, C. R., Flores, F. J., Aguilera Real, M. E., Fajardo-Campos, P., Violante Ortiz, R. M., Luna Ceballos, R. I., Duran-Barragan, S., Zytkiewicz-Jaruga, D., Krzyzagorska, E., Skokowska, E., Klodawska, K., Mordaka, R., Mazur, S., Stasinska, T., Sulowicz, W., Constantin, C., Negru, D., Paveliu, F. S., Negrisanu, G. D., Szilagyi, I., Busegeanu, M. M. G., Pena, M. C., Avram, R. I., Ardelean, S. L., Ilavska, A., Dzupina, A., Oroszova, A., Kolesarova, E., Obetkova, I., Smatanova, I., Babikova, J., Fulop, P., Haffner, R., Rayner, B. L., Kruger, D. S., Urbach, D. V., Mitha, E., Vally Mahomed Latiff, G. H., Makan, H., Du Plessis, H., Jurgens, J. C., Reddy, J., Trokis, J. S., McHarry, K., Distiller, L. A., Mayet, L., Burgess, L. J., Van Zyl, L. J., Joshi, M. P., Sebastian, P. J., Du Toit, S. M., Blignaut, S. C., Serrano, A. G., Morales, C., Poch, E., Mosquera, E. M., Castro, F. C., Gonzalez Martinez, F. J., Perez-Contreras, F. J., Fernandez-Fresnedo, G., Garcia Mendez, I. F., Perez, J. P., Martinez, J. C., Gorriz Teruel, J. L., Nieto Iglesias, L. J., Munoz-Torres, M., Munar Vila, M. A., Arenas Jimenez, M. D., Dominguez-Lopez, M. E., Val, M. H., Terrades, N. R., Olmo, R. S., Malek Marin, T. G., Arif, A. A., Lee, B. J., Mehta, B. R., Baker, B. H., Jere, C. S., Bains, D. G., Stricklin, D. G., Cheung, D., Echeverri, D., Vera, E., Heurich, E. M., Sterba, G. A., Hernandez, G. T., Paez, H. E., Acosta, I. A., Ahmed, I., Sachmechi, I., Madu, I. J. E., Obhrai, J. S., Hammoud, J. A., Tumlin, J. A., Cain, J., Moya-Hechevarria, J., Connaire, J. J., Haggiagi, J., Odren, J. A., Bellucci-Jackson, J. M., Yan, J., Parker, J. C., Tolins, J. P., Gomez-Cortes, J. D., Cardona, J. F., Mandry, J. M., Olivero, J. J., Hendon, K. S., Kaveh, K., Kooienga, L. A., Bermudez, L. R., Rich, L. M., Gold, M., Gonzalez, M., Schaefer, M. E., Welch, M., Moustafa, M. A., Mussaji, M., Pergola, P. E., Phaosawasdi, P., Silva, R. A., Presas, R., Lynn, R. I., Kronfli, S. J., Ventrapragada, S. V., Niranjan, S. N., Husain, S., Satko, S., Jabbour, S. A., Rovner, S. F., Gouge, S. F., Joshi, S. S., Ramachandran Subramanian, V. B., Lane, W., Calhoun, W. & Durham, W., 1 May 2024, In: Journal of the American Society of Nephrology. 35, 5, p. 594-606 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Prevalence, awareness, treatment, and control of hypertension in community-dwelling older adults with chronic kidney disease: the Irish longitudinal study on ageing

    Browne, L. D., Alamin, M. Y., Miri, H. H., Hall, R., Tandan, M., Sexton, D. & Stack, A. G., 1 Aug 2024, In: Clinical Kidney Journal. 17, 8, sfae184.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function

    Macdougall, I. C., Ponikowski, P., Stack, A. G., Wheeler, D. C., Anker, S. D., Butler, J., Filippatos, G., Göhring, U. M., Kirwan, B. A., Kumpeson, V., Metra, M., Rosano, G., Ruschitzka, F., van der Meer, P., Wächter, S. & Jankowska, E. A., Sep 2023, In: Clinical Journal of the American Society of Nephrology. 18, 9, p. 1124-1134 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Impact of serum sodium concentrations, and effect modifiers on mortality in the Irish Health System

    Walsh, C., Browne, L. D., Gilligan, R., Galvin, R., Glynn, L., Walsh, C. & Stack, A. G., Dec 2023, In: BMC Nephrology. 24, 1, p. 203 203.

    Research output: Contribution to journalArticlepeer-review

    Open Access