Personal profile
Research Interests
Proteases and protease inhibitors; Streptococcus pyogenes; protein structure
Fingerprint
Dive into the research topics where Jakki Cooney is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
The 1.7 Å crystal structure of the C5a peptidase from Streptococcus agalactiae (ScpB) reveals an active site competent for catalysis
Cullen, R., Teçza, M., Miclot, T., Behan, S., Jain, M., Avink, M. K., Cooney, J. C. & Kagawa, T. F., Mar 2024, In: Proteins: Structure, Function and Genetics. 92, 3, p. 427-431 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparative diet-gut microbiome analysis in Crohn’s disease and Hidradenitis suppurativa
Cronin, P., McCarthy, S., Hurley, C., Ghosh, T. S., Cooney, J. C., Tobin, A. M., Murphy, M., O’Connor, E. M., Shanahan, F. & O’Toole, P. W., 2023, In: Frontiers in Microbiology. 14, 1289374.Research output: Contribution to journal › Article › peer-review
Open Access -
The protease associated (PA) domain in ScpA from Streptococcus pyogenes plays a role in substrate recruitment
McKenna, S., Aylward, F., Miliara, X., Lau, R. J., Huemer, C. B., Giblin, S. P., Huse, K. K., Liang, M., Reeves, L., Pearson, M., Xu, Y., Rouse, S. L., Pease, J. E., Sriskandan, S., Kagawa, T. F., Cooney, J. & Matthews, S., 1 Nov 2023, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1871, 6, 140946.Research output: Contribution to journal › Article › peer-review
Open Access -
X-ray diffraction data for the C5a-peptidase mutant with modified activity and specificity
Kagawa, T. F., Jain, M. & Cooney, J. C., Feb 2023, In: Data in Brief. 46, 108778.Research output: Contribution to journal › Article › peer-review
Open Access -
Exosite binding modulates the specificity of the immunomodulatory enzyme ScpA, a C5a inactivating bacterial protease
Jain, M., Teçza, M., Kagawa, T. F. & Cooney, J. C., Jan 2022, In: Computational and Structural Biotechnology Journal. 20, p. 4860-4869 10 p.Research output: Contribution to journal › Article › peer-review
Open Access