Raffaele Nicastro
20132024

Research activity per year

Personal profile

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • Spermidine is essential for fasting-mediated autophagy and longevity

    Hofer, S. J., Daskalaki, I., Bergmann, M., Friščić, J., Zimmermann, A., Mueller, M. I., Abdellatif, M., Nicastro, R., Masser, S., Durand, S., Nartey, A., Waltenstorfer, M., Enzenhofer, S., Faimann, I., Gschiel, V., Bajaj, T., Niemeyer, C., Gkikas, I., Pein, L. & Cerrato, G. & 36 others, Pan, H., Liang, Y., Tadic, J., Jerkovic, A., Aprahamian, F., Robbins, C. E., Nirmalathasan, N., Habisch, H., Annerer, E., Dethloff, F., Stumpe, M., Grundler, F., Wilhelmi de Toledo, F., Heinz, D. E., Koppold, D. A., Rajput Khokhar, A., Michalsen, A., Tripolt, N. J., Sourij, H., Pieber, T. R., de Cabo, R., McCormick, M. A., Magnes, C., Kepp, O., Dengjel, J., Sigrist, S. J., Gassen, N. C., Sedej, S., Madl, T., De Virgilio, C., Stelzl, U., Hoffmann, M. H., Eisenberg, T., Tavernarakis, N., Kroemer, G. & Madeo, F., Sep 2024, In: Nature Cell Biology. 26, 9, p. 1571-1584 14 p.

    Research output: Contribution to journalArticlepeer-review

  • The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes

    Füllbrunn, N., Nicastro, R., Mari, M., Griffith, J., Herrmann, E., Rasche, R., Borchers, A.-C., Auffarth, K., Kümmel, D., Reggiori, F., De Virgilio, C., Langemeyer, L. & Ungermann, C., 3 Jun 2024, In: Journal of Cell Biology. 223, 6

    Research output: Contribution to journalArticlepeer-review

  • Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor

    Nicastro, R., Brohée, L., Alba, J., Nüchel, J., Figlia, G., Kipschull, S., Gollwitzer, P., Romero-Pozuelo, J., Fernandes, S. A., Lamprakis, A., Vanni, S., Teleman, A. A., De Virgilio, C. & Demetriades, C., Sep 2023, In: Nature Cell Biology. 25, 9, p. 1303-1318 16 p.

    Research output: Contribution to journalArticlepeer-review

  • Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation

    Caligaris, M., Nicastro, R., Hu, Z., Tripodi, F., Hummel, J. E., Pillet, B., Deprez, M.-A., Winderickx, J., Rospert, S., Coccetti, P., Dengjel, J. & De Virgilio, C., 7 Feb 2023, In: eLife. 12

    Research output: Contribution to journalArticlepeer-review

  • The Yeast Protein Kinase Sch9 Functions as a Central Nutrient-Responsive Hub That Calibrates Metabolic and Stress-Related Responses

    Caligaris, M., Sampaio-Marques, B., Hatakeyama, R., Pillet, B., Ludovico, P., De Virgilio, C., Winderickx, J. & Nicastro, R., 26 Jul 2023, In: Journal of Fungi. 9, 8

    Research output: Contribution to journalReview articlepeer-review