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Raffaele Nicastro

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Raffaele Nicastro

Dr.

 https://orcid.org/0000-0002-5420-2228

Accepting PhD Students

20132025

Research activity per year

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  • TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89

    Nicastro, R., Péli-Gulli, M. P., Caligaris, M., Jaquenoud, M., Dokládal, L., Alba, J., Tripodi, F., Pillet, B., Brunner, M., Stumpe, M., Muneshige, K., Hatakeyama, R., Dengjel, J. & De Virgilio, C., 27 May 2025, In: Cell Reports. 44, 5, 115683.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Spermidine is essential for fasting-mediated autophagy and longevity

    Hofer, S. J., Daskalaki, I., Bergmann, M., Friščić, J., Zimmermann, A., Mueller, M. I., Abdellatif, M., Nicastro, R., Masser, S., Durand, S., Nartey, A., Waltenstorfer, M., Enzenhofer, S., Faimann, I., Gschiel, V., Bajaj, T., Niemeyer, C., Gkikas, I., Pein, L. & Cerrato, G. & 36 others, Pan, H., Liang, Y., Tadic, J., Jerkovic, A., Aprahamian, F., Robbins, C. E., Nirmalathasan, N., Habisch, H., Annerer, E., Dethloff, F., Stumpe, M., Grundler, F., Wilhelmi de Toledo, F., Heinz, D. E., Koppold, D. A., Rajput Khokhar, A., Michalsen, A., Tripolt, N. J., Sourij, H., Pieber, T. R., de Cabo, R., McCormick, M. A., Magnes, C., Kepp, O., Dengjel, J., Sigrist, S. J., Gassen, N. C., Sedej, S., Madl, T., De Virgilio, C., Stelzl, U., Hoffmann, M. H., Eisenberg, T., Tavernarakis, N., Kroemer, G. & Madeo, F., Sep 2024, In: Nature Cell Biology. 26, 9, p. 1571-1584 14 p.

    Research output: Contribution to journal › Article › peer-review

  • The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes

    Füllbrunn, N., Nicastro, R., Mari, M., Griffith, J., Herrmann, E., Rasche, R., Borchers, A.-C., Auffarth, K., Kümmel, D., Reggiori, F., De Virgilio, C., Langemeyer, L. & Ungermann, C., 3 Jun 2024, In: Journal of Cell Biology. 223, 6, e202305038.

    Research output: Contribution to journal › Article › peer-review

  • Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor

    Nicastro, R., Brohée, L., Alba, J., Nüchel, J., Figlia, G., Kipschull, S., Gollwitzer, P., Romero-Pozuelo, J., Fernandes, S. A., Lamprakis, A., Vanni, S., Teleman, A. A., De Virgilio, C. & Demetriades, C., Sep 2023, In: Nature Cell Biology. 25, 9, p. 1303-1318 16 p.

    Research output: Contribution to journal › Article › peer-review

  • Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation

    Caligaris, M., Nicastro, R., Hu, Z., Tripodi, F., Hummel, J. E., Pillet, B., Deprez, M.-A., Winderickx, J., Rospert, S., Coccetti, P., Dengjel, J. & De Virgilio, C., 7 Feb 2023, In: eLife. 12

    Research output: Contribution to journal › Article › peer-review

View all 22 research outputs