Personal profile
Research Interests
Food protein ingredients,Functional food ingredients/nutraceuticals,Food protein chemistry/biochemistry,Enzymatic hydrolysis of food proteins, Enzymatic cross-linking of food proteins, Purification and characterisation of starter culture-derived aminopeptidases, Role of aminopeptidases in food protein hydrolysate debittering.
Biography
Education: BSc in Biochemistry (National University of Ireland) PhD protein chemistry/enzymology (National University of Ireland) Employment history:
- Research Fellow - Food Science Department, North Carolina State University, USA and; at the Food Biotechnology Centre, University College, Cork.
- Senior Research Officer - Chemistry Department, Teagasc, Moorepark.
- Lecturer, Senior Lecturer and Associate Professor - Department of Life Sciences, University of Limerick.
- Professor (personal chair) of Food Protein-Derived Bioactive Peptides - Department of Biological Sciences, University of Limerick
- Food protein chemistry/biochemistry.
- Food protein ingredients (extraction of proteins from different sources - animal, plant and marine proteins).
- Generation and characterisation of enzymatic hydrolysates of food proteins using microbial, mammalian and plant derived food-grade proteinase and peptidase preparations.
- Characterisation of the functional properties of food proteins and their enzymatic hydrolysates, e.g., solubility, heat stability, emulsification, foaming, turbidity, viscosity properties.
- Bioactive peptides/nutraceuticals, i.e., enzymatic generation, characterisation and identification (LC-MS/MS) of bioactive peptides having blood pressure reducing, serum glucose regulation, antioxidant, immune-modulatory, mineral binding, etc, properties.
- LC-MS/MS-based characterisation of the hydrolytic specificity of different enzyme activities on purified food protein substrates.
- Enzymatic cross-linking (using transglutaminase) of food proteins and their hydrolysates.
- Role of microbial and mammalian exopeptidases in food protein hydrolysate debittering.
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Collaborations and top research areas from the last five years
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Identification, characterization and resistance to digestion assessment of hemp-derived dipeptidyl-peptidase IV inhibitory peptides
Amigo-Benavent, M., Rivero-Pino, F., Villanueva-Lazo, A., Montserrat-de la Paz, S., FitzGerald, R. J. & Millan-Linares, M. C., 12 Jan 2026, In: Food and Function. 17, 1, p. 577-587 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Bioactive peptides in cosmetic formulations: Review of current in vitro and ex vivo evidence
van Walraven, N., FitzGerald, R. J., Danneel, H. J. & Amigo-Benavent, M., Nov 2025, In: Peptides. 193, 171440.Research output: Contribution to journal › Review article › peer-review
Open Access -
Blue Whiting (Micromesistius poutassou) Protein Hydrolysates Elicit Hydrolytic Enzyme-Dependent Improvements in Acute Postprandial Blood Glucose and Pancreatic Islet Health in a High-Fat Fed Diet-Induced Obese Mouse Model
Sharkey, S. J., Lafferty, R. A., Harnedy-Rothwell, P. A., Gite, S., Whooley, J., Allsopp, P. J., FitzGerald, R. J. & O’Harte, F. P. M., 20 Jun 2025, In: ACS Food Science and Technology. 5, 6, p. 2237-2249 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Emulsification Properties of Plant and Milk Protein Concentrate Blends
Khalesi, M., Dowling, S., Comerford, J., Sweeney, C., Esteghlal, S. & FitzGerald, R. J., Oct 2025, In: Foods. 14, 19, 3406.Research output: Contribution to journal › Article › peer-review
Open Access -
Enhancement of the In Vitro Bioactivities of Limpet (Patella vulgata) Proteins: Effect of Pre-Enzymatic Hydrolysis Followed by Simulated Gastrointestinal Digestion
Bilir, G., Cermeño, M., Khalesi, M., Ekinci, D. & FitzGerald, R. J., Dec 2025, In: Food and Bioprocess Technology. 18, 12, p. 10620-10635 16 p.Research output: Contribution to journal › Article › peer-review