Personal profile

Research Interests

The Hudson group focuses on the manipulation of the physicochemical properties of small and large active molecules to improve their stability, solubility and dissolution rates with the ultimate goal of improving the bioavailability of active pharmaceutical ingredients. They explore the solution and solid state behaviour of these molecules both during formulation/manufacture into medicines and in biorelevant environments. Their research focuses on the thermodynamics behind aggregation, crystallisation and precipitation in a range of solvents and bio relevant media and develops formulations and structures to control this solution/solid state behaviour. Current Postdoctoral researchers:Dr Jhimli PaulguinDr Poonam RatreyDr Shasha JinCurrent PhD students: Mariana Silva (Marie Curie ITN, Janssen), Amabille Kloc (Marie Curie ITN, TUD, Janssen), Peuli Ghosh (SFI, SSPC), Parth Joshi (PMTC, Allergen), Mariana Diniz (SFI, SSPC), Marta Bergillos (SFI, SSPC), Harsh Barua (SFI, SSPC), Camila Viera (SFI, New Frontiers), Mateo Flores Naranjo (SFI, New Frontiers), Francisco Duarte (IRC), Sara Fatima (SFI, co-supervised with Jennifer Cookman), Former PhD students: Dr Teresa Tierney (IRCSET, SSPC), Dr Raquel Arribas Bueno (SFI SSPC), Dr Pauric Bannigan (SFI CDA),  Dr Vivek Verma (SFI SSPC), Dr Katalin Bodnar (SFI SSPC), Dr Ajay Kumar (SFI, SSPC), Dr Michele Dully (IRC, COOK Medical), Dr James Flynn (SFI, CDA), Dr Sally Ryan (SFI, Curam), Dr Miriama Ceresnakova (IRC, COOK Medical), Dr Aoibhin Ryan (IRC), Former Masters students: Sarah Mallen (SFI CDA),  Tracey Carroll (Sanofi Genzyme),  Former Postdocs:Dr Gesmi Mikovich (SFI CDA), Dr Edel Durack (SFI CDA), Dr Aisling Lynch (SFI SSPC), Dr Ajay Kumar (SFI, SSPC), Dr Malgorzata Tecza (DTIF, EI), Dr Pratikkumar Patel, Dr Promita Bhattacharjee, Dr Vinay Gedi.

Teaching Interests

Sarah is a lecturer in Physical and General Chemistry to undergraduate chemistry students. She also is coordinator for the core chemistry curriculum for training second level chemistry teachers, including chemistry pedagogy. She has engaged in peer observation exercises with colleagues from the Civil and Mechanical engineering departments and have worked on integrating their suggestions for problem based and self directed learning into her own teaching style. She engages with technology during lectures, where advantageous and appropriate, e.g. using clicker quizzes to motivate student participation and promote class discussion on topics. Her ambition is to stimulate a passion, or at least a curiosity, in her students and strives to do this by emphasizing the importance and relevance of each topic for life and their education.

Biography

Sarah studied Chemistry in Trinity College Dublin were she was a Trinity Foundation Scholarandnbsp;and where she did aandnbsp;research masters on the synthesis of a family of Re (I) metal complexes and a study of their photophysical properties with Prof John Kelly. Her PhD in theandnbsp;University of Limerickandnbsp;focussed onandnbsp;the immobilization of enzymes onto novel mesoporous supports and their catalytic properties with Prof Edmond Magner, Prof Kieran Hodnett and Dr Jakkiandnbsp;Cooney. She secured a Marie Curie Outgoing Internationalandnbsp;Fellowship to work with Prof Robert Langer in MIT, USA. There she developedandnbsp;in situandnbsp;crosslinkable hydrogel systems for cartilage regeneration and drug delivery and she also studied the biocompatibility (in vivoandnbsp;andandnbsp;in vitro) of micro- and nano- mesoporous silica particles. After this fellowship, Sarah worked in Waterford Institute of Technology on the identification of the mechanisms and causes of tablet splitting within the Genzyme Ireland facility.andnbsp;Since November 2011, Sarah has been a lecturer in Chemistry in the Department of Chemical Sciences and a researcher in the Bernal Institute in the University of Limerick. She is a principal investigator in the Science Foundation Irelandandnbsp;Research Centre for Pharmaceuticals (SSPC) since 2013. andnbsp;

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 9 - Industry, Innovation, and Infrastructure

Education/Academic qualification

Diploma, Diploma

Award Date: 1 Jan 2013

PhD, PhD

Award Date: 1 Jan 2006

Masters, Masters by research, Trinity College Dublin

Award Date: 1 Jan 2000

Bachelor, BA (Mod), Trinity College Dublin

Award Date: 1 Jan 1999

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