TY - JOUR
T1 - A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers
AU - Shuhaibar, M.
AU - Walsh, C.
AU - Lindsay, F.
AU - Lee, N.
AU - Walsh, P.
AU - O'Gorman, P.
AU - Boran, G.
AU - McLoughlin, R.
AU - Qasim, A.
AU - Breslin, N.
AU - Ryan, B.
AU - O'Connor, H.
AU - O'Morain, C.
PY - 2011/3
Y1 - 2011/3
N2 - Background: The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening. Methods: A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy. Results: A total of 909 faecal testing kits were distributed. Age range was 53-60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polypsand CRCin37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016). Conclusion: The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.
AB - Background: The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening. Methods: A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy. Results: A total of 909 faecal testing kits were distributed. Age range was 53-60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polypsand CRCin37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016). Conclusion: The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.
KW - Adenomas
KW - Colorectal cancer (CRC)
KW - FIT (faecal immunochemical testing)
KW - GFOBT (gauaic faecal occult blood test)
KW - Outcomes
KW - Screening
KW - Uptake rates
UR - http://www.scopus.com/inward/record.url?scp=79954438738&partnerID=8YFLogxK
U2 - 10.1007/s11845-010-0605-0
DO - 10.1007/s11845-010-0605-0
M3 - Article
C2 - 20953981
AN - SCOPUS:79954438738
SN - 0021-1265
VL - 180
SP - 103
EP - 108
JO - Irish Journal of Medical Science
JF - Irish Journal of Medical Science
IS - 1
ER -
