TY - JOUR
T1 - A curious case of cough in a young woman
AU - Di Giovanni, Bennett
AU - Newmarch, W.
AU - Weiler, M.
AU - Casserly, B.
AU - Scanlon, T.
N1 - Publisher Copyright:
© 2019, Irish Medical Association. All rights reserved.
PY - 2019/4
Y1 - 2019/4
N2 - Inflammatory myofibroblastic tumour (IMT) is a rare neoplasm derived from tissue of mesenchymal origin. This tumour occurs predominantly in the lung, though extrapulmonary sites have been documented throughout the body.1 Presentation can be variable depending on location of the tumour and can include constitutional symptoms (fever, weight loss), thrombocytosis, hypergammaglobulinemia, anemia, and mass effect on local structures.2 Majority of patients with intrapulmonary IMT remain asymptomatic but can have symptoms including chest pain, dyspnoea, cough or haemoptysis.3 Most cases of IMT present in younger individuals (under age 40).4 Although the aetiology of IMT is unclear, current hypotheses suggest an inflammatory response to infection or an underlying malignancy could promote such cellular changes. Alternatively, the inflammatory component itself may be a consequence of the development of these mesenchymal tumours.
AB - Inflammatory myofibroblastic tumour (IMT) is a rare neoplasm derived from tissue of mesenchymal origin. This tumour occurs predominantly in the lung, though extrapulmonary sites have been documented throughout the body.1 Presentation can be variable depending on location of the tumour and can include constitutional symptoms (fever, weight loss), thrombocytosis, hypergammaglobulinemia, anemia, and mass effect on local structures.2 Majority of patients with intrapulmonary IMT remain asymptomatic but can have symptoms including chest pain, dyspnoea, cough or haemoptysis.3 Most cases of IMT present in younger individuals (under age 40).4 Although the aetiology of IMT is unclear, current hypotheses suggest an inflammatory response to infection or an underlying malignancy could promote such cellular changes. Alternatively, the inflammatory component itself may be a consequence of the development of these mesenchymal tumours.
KW - Inflammatory myofibroblastic tumour
KW - Inflammatory pseudotumor
UR - http://www.scopus.com/inward/record.url?scp=85068116030&partnerID=8YFLogxK
M3 - Article
C2 - 31190516
AN - SCOPUS:85068116030
SN - 0332-3102
VL - 112
SP - 920
JO - Irish Medical Journal
JF - Irish Medical Journal
IS - 4
ER -