A mathematical model of exoprotein production in bacteria

K. D. Coleman, A. C. Fowler

Research output: Contribution to journalArticlepeer-review

Abstract

We present a simple mathematical model for the synthesis of extracellular proteins by a class of bacteria which secrete significant quantities of this exoprotein in late-exponential and stationary phases. This model is the simplest generalization of Michaelis-Menten kinetics (the Monod model) and agrees well with laboratory experiments in batch culture. The model may serve as a simple prototype for the analysis of certain virulent bacterial infections in vivo, particularly that of Pseudomonas aeruginosa in burn wounds.

Original languageEnglish
Pages (from-to)77-94
Number of pages18
JournalMathematical Medicine and Biology
Volume1
Issue number1
DOIs
Publication statusPublished - 1984
Externally publishedYes

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