Abstract
We present a simple mathematical model for the synthesis of extracellular proteins by a class of bacteria which secrete significant quantities of this exoprotein in late-exponential and stationary phases. This model is the simplest generalization of Michaelis-Menten kinetics (the Monod model) and agrees well with laboratory experiments in batch culture. The model may serve as a simple prototype for the analysis of certain virulent bacterial infections in vivo, particularly that of Pseudomonas aeruginosa in burn wounds.
Original language | English |
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Pages (from-to) | 77-94 |
Number of pages | 18 |
Journal | Mathematical Medicine and Biology |
Volume | 1 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1984 |
Externally published | Yes |