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A preclinical evaluation of the PI3K alpha/delta dominant inhibitor BAY 80-6946 in HER2-positive breast cancer models with acquired resistance to the HER2-targeted therapies trastuzumab and lapatinib

  • N. Elster
  • , M. Cremona
  • , C. Morgan
  • , S. Toomey
  • , A. Carr
  • , A. O’Grady
  • , B. T. Hennessy
  • , A. J. Eustace
  • Royal College of Surgeons in Ireland

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Pharmacology, Toxicology and Pharmaceutical Science