Acute reduction of lower-body contractile function following a microbiopsy of m. vastus lateralis

Robert W. Davies, Brian P. Carson, Joseph J. Bass, Sorcha Holohan, Philip M. Jakeman

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty-three resistance trained men 18-35 years (23 [3] years, 1.8 [0.1] m, 81 [10] kg body mass, 2.3 [1.1] years resistance training experience; mean [SD]) performed repeated maximal voluntary isometric squats (ISQ) and countermovement jumps (CMJ) pre- and +30 minutes post a unilateral microbiopsy of m. vastus lateralis. ISQ and CMJ were simultaneously measured by two force plates sampling ipsilateral (biopsied) and contralateral (non-biopsied) limb force. Bilateral limb force (ipsilateral + contralateral) and imbalance (ipsilateral/bilateral) data are reported as % change from pre-biopsy (mean [95% CI]). A post-biopsy reduction in bilateral ISQ peak force (−17 [−23, −11] %; P < 0.001), ISQ rate of force development (RFD; −28 [−41, −15] %, P = 0.002) and CMJ peak take-off force (−7 [−13, −1]%, P = 0.019) occurred. Imbalance was observed for ISQ peak force (3.2 [2.1, 4.3] %, P < 0.001), RFD (2.8 [1.6, 4.0] %, P < 0.001) and CMJ landing (3.3 [1.0, 5.6] %, P = 0.009), resultant of a force transfer from the ipsilateral (biopsied) to the contralateral (non-biopsied) limb. These data suggest that in young, resistance trained men a modulatory influence on maximal voluntary static and dynamic lower-body contractile function is evoked acutely (+30 minutes) following a microbiopsy of m. vastus lateralis.

Original languageEnglish
Pages (from-to)2638-2642
Number of pages5
JournalScandinavian Journal of Medicine and Science in Sports
Volume28
Issue number12
DOIs
Publication statusPublished - Dec 2018

Keywords

  • biopsy
  • human
  • muscle contraction
  • muscle strength
  • quadriceps muscle

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