TY - JOUR
T1 - Angiotensin Converting Enzyme and Dipeptidyl Peptidase-IV Inhibitory, and Antioxidant Activities of a Blue Mussel (Mytilus edulis) Meat Protein Extract and Its Hydrolysates
AU - Neves, Adriana C.
AU - Harnedy, Pádraigín A.
AU - FitzGerald, Richard J.
N1 - Publisher Copyright:
© 2016 Taylor & Francis.
PY - 2016/11/16
Y1 - 2016/11/16
N2 - Protein extracted from mussel processing coproducts was hydrolyzed with four different food-grade enzyme preparations and assessed for angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) inhibitory and oxygen radical antioxidant capacity (ORAC) activities. All hydrolysates tested showed higher activity than the intact protein. ACE and DPP-IV IC50 values in the range 1.13–3.34 and 0.33–2.43 mg mL−1, respectively, and ORAC values in the range 66.26–121.56 µmol trolox equivalents g–1 were obtained. These results suggest that some of the mussel meat protein hydrolysates may have potential as functional food ingredients for the management of diseases such as type II diabetes and hypertension.
AB - Protein extracted from mussel processing coproducts was hydrolyzed with four different food-grade enzyme preparations and assessed for angiotensin converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) inhibitory and oxygen radical antioxidant capacity (ORAC) activities. All hydrolysates tested showed higher activity than the intact protein. ACE and DPP-IV IC50 values in the range 1.13–3.34 and 0.33–2.43 mg mL−1, respectively, and ORAC values in the range 66.26–121.56 µmol trolox equivalents g–1 were obtained. These results suggest that some of the mussel meat protein hydrolysates may have potential as functional food ingredients for the management of diseases such as type II diabetes and hypertension.
KW - angiotensin converting enzyme
KW - dipeptidyl peptidase-IV
KW - hydrolysis
KW - Mussel meat
KW - oxygen radical absorbance capacity
UR - http://www.scopus.com/inward/record.url?scp=84992034563&partnerID=8YFLogxK
U2 - 10.1080/10498850.2015.1051259
DO - 10.1080/10498850.2015.1051259
M3 - Article
AN - SCOPUS:84992034563
SN - 1049-8850
VL - 25
SP - 1221
EP - 1233
JO - Journal of Aquatic Food Product Technology
JF - Journal of Aquatic Food Product Technology
IS - 8
ER -