TY - JOUR
T1 - Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms
AU - Romário-Silva, Diego
AU - Franchin, Marcelo
AU - Alencar, Severino Matias
AU - Bueno-Silva, Bruno
AU - Sardi, Janaína de Cássia Orlandi
AU - da Silva, Andréa Cristina Barbosa
AU - Cruz-Vieira, Fabiane
AU - da Silva, Priscila Vieira
AU - Rosalen, Pedro Luiz
N1 - Publisher Copyright:
© The Author(s) under exclusive licence to Sociedade Brasileira de Microbiologia 2024.
PY - 2024/9
Y1 - 2024/9
N2 - Objective: To evaluate the antimicrobial activity of Brazilian honeys against oral microorganisms. Design: Organic honeys (OH-1 to OH-8) were diluted (%-w/v) and sterilized by filtration. Antimicrobial activity was defined by determining MIC and CBM against oral Streptococcus. The component responsible for the antimicrobial action was defined by a catalase assay. Antibiofilm activity was evaluated against the monospecies biofilm of Streptococcus mutans (ATCC 700610). Results: OHs showed antimicrobial activity principally OH-1, OH-2, OH-3, and OH-7 with MIC values ranging between 10 and 25%. The mechanism of action occurs mainly by hydrogen peroxide produced by honey enzymes. OH-1, OH-2, and OH-7 showed total biofilm destruction at low concentrations. Conclusion: Brazilian honeys have promising antimicrobial and antibiofilm activity with the potential to control oral microbiota.
AB - Objective: To evaluate the antimicrobial activity of Brazilian honeys against oral microorganisms. Design: Organic honeys (OH-1 to OH-8) were diluted (%-w/v) and sterilized by filtration. Antimicrobial activity was defined by determining MIC and CBM against oral Streptococcus. The component responsible for the antimicrobial action was defined by a catalase assay. Antibiofilm activity was evaluated against the monospecies biofilm of Streptococcus mutans (ATCC 700610). Results: OHs showed antimicrobial activity principally OH-1, OH-2, OH-3, and OH-7 with MIC values ranging between 10 and 25%. The mechanism of action occurs mainly by hydrogen peroxide produced by honey enzymes. OH-1, OH-2, and OH-7 showed total biofilm destruction at low concentrations. Conclusion: Brazilian honeys have promising antimicrobial and antibiofilm activity with the potential to control oral microbiota.
UR - https://doi.org/10.1007/s42770-024-01343-9
U2 - 10.1007/s42770-024-01343-9
DO - 10.1007/s42770-024-01343-9
M3 - Article
VL - 55
SP - 2285
EP - 2292
JO - Brazilian Journal of Microbiology
JF - Brazilian Journal of Microbiology
IS - 3
ER -