Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts: A cell-based point of view

Mariana Araújo Vieira do Carmo; Daniel Granato; Luciana Azevedo

doi:10.1016/bs.afnr.2021.02.010

Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts: A cell-based point of view

Mariana Araújo Vieira do Carmo
, Daniel Granato
, Luciana Azevedo

Universidade Federal de Alfenas

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Phenolic compounds have demonstrated several in vitro beneficial properties by acting as antioxidant and pro-oxidant agents. This chapter approaches the relationship among oxidative stress, cancer, phenolic compounds and antiproliferative activity. Moreover, it discusses in vitro techniques and their biological applications, regarding cell viability and intracellular measure of reactive oxygen assays. The in vitro methods are important tools for screening and understanding the pathways involved on antiproliferative and antioxidant/pro-oxidant effects of phenolic compounds. These findings open avenues for the development of innovative food, chemical structures, technological applications and future perspectives in this research field.

Original language	English
Title of host publication	Application of Polyphenols in Foods and Food Models
Editors	Daniel Granato
Publisher	Academic Press Inc.
Pages	253-280
Number of pages	28
ISBN (Print)	9780128225066
DOIs	https://doi.org/10.1016/bs.afnr.2021.02.010
Publication status	Published - Jan 2021

Publication series

Name	Advances in Food and Nutrition Research
Volume	98
ISSN (Print)	1043-4526

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer
Cell culture
Cell viability
In vitro methods
Oxidative stress
Phenolic compounds
Reactive oxygen species

Access to Document

10.1016/bs.afnr.2021.02.010

Cite this

do Carmo, M. A. V., Granato, D., & Azevedo, L. (2021). Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts: A cell-based point of view. In D. Granato (Ed.), Application of Polyphenols in Foods and Food Models (pp. 253-280). (Advances in Food and Nutrition Research; Vol. 98). Academic Press Inc.. https://doi.org/10.1016/bs.afnr.2021.02.010

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title = "Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts: A cell-based point of view",

abstract = "Phenolic compounds have demonstrated several in vitro beneficial properties by acting as antioxidant and pro-oxidant agents. This chapter approaches the relationship among oxidative stress, cancer, phenolic compounds and antiproliferative activity. Moreover, it discusses in vitro techniques and their biological applications, regarding cell viability and intracellular measure of reactive oxygen assays. The in vitro methods are important tools for screening and understanding the pathways involved on antiproliferative and antioxidant/pro-oxidant effects of phenolic compounds. These findings open avenues for the development of innovative food, chemical structures, technological applications and future perspectives in this research field.",

keywords = "Cancer, Cell culture, Cell viability, In vitro methods, Oxidative stress, Phenolic compounds, Reactive oxygen species",

author = "\{do Carmo\}, \{Mariana Ara{\'u}jo Vieira\} and Daniel Granato and Luciana Azevedo",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

month = jan,

doi = "10.1016/bs.afnr.2021.02.010",

language = "English",

isbn = "9780128225066",

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Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts: A cell-based point of view. / do Carmo, Mariana Araújo Vieira; Granato, Daniel; Azevedo, Luciana.
Application of Polyphenols in Foods and Food Models. ed. / Daniel Granato. Academic Press Inc., 2021. p. 253-280 (Advances in Food and Nutrition Research; Vol. 98).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts

T2 - A cell-based point of view

AU - do Carmo, Mariana Araújo Vieira

AU - Granato, Daniel

AU - Azevedo, Luciana

PY - 2021/1

Y1 - 2021/1

N2 - Phenolic compounds have demonstrated several in vitro beneficial properties by acting as antioxidant and pro-oxidant agents. This chapter approaches the relationship among oxidative stress, cancer, phenolic compounds and antiproliferative activity. Moreover, it discusses in vitro techniques and their biological applications, regarding cell viability and intracellular measure of reactive oxygen assays. The in vitro methods are important tools for screening and understanding the pathways involved on antiproliferative and antioxidant/pro-oxidant effects of phenolic compounds. These findings open avenues for the development of innovative food, chemical structures, technological applications and future perspectives in this research field.

AB - Phenolic compounds have demonstrated several in vitro beneficial properties by acting as antioxidant and pro-oxidant agents. This chapter approaches the relationship among oxidative stress, cancer, phenolic compounds and antiproliferative activity. Moreover, it discusses in vitro techniques and their biological applications, regarding cell viability and intracellular measure of reactive oxygen assays. The in vitro methods are important tools for screening and understanding the pathways involved on antiproliferative and antioxidant/pro-oxidant effects of phenolic compounds. These findings open avenues for the development of innovative food, chemical structures, technological applications and future perspectives in this research field.

KW - Cancer

KW - Cell culture

KW - Cell viability

KW - In vitro methods

KW - Oxidative stress

KW - Phenolic compounds

KW - Reactive oxygen species

UR - https://www.scopus.com/pages/publications/85102286082

U2 - 10.1016/bs.afnr.2021.02.010

DO - 10.1016/bs.afnr.2021.02.010

M3 - Chapter

C2 - 34507644

AN - SCOPUS:85102286082

SN - 9780128225066

T3 - Advances in Food and Nutrition Research

SP - 253

EP - 280

BT - Application of Polyphenols in Foods and Food Models

A2 - Granato, Daniel

PB - Academic Press Inc.

ER -

Antioxidant/pro-oxidant and antiproliferative activities of phenolic-rich foods and extracts: A cell-based point of view

Abstract

Publication series

UN SDGs

Keywords

Access to Document

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