Artemisia scoparia attenuates amyloid β accumulation and tau hyperphosphorylation in spontaneously hypertensive rats

Kitipong Promyo; Jeong Yong Cho; Kyung Hee Park; Lily Jaiswal; Sun Young Park; Kyung Sik Ham

doi:10.1007/s10068-017-0077-3

Artemisia scoparia attenuates amyloid β accumulation and tau hyperphosphorylation in spontaneously hypertensive rats

Kitipong Promyo
, Jeong Yong Cho
, Kyung Hee Park
, Lily Jaiswal
, Sun Young Park
, Kyung Sik Ham

Department of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The preventive effects of Artemisia scoparia extract (AS) and AS + garlic extract (ASG) on the risk of Alzheimer’s disease (AD) were evaluated in spontaneously hypertensive rats. Rats were supplemented with diets containing 2% (w/w) of AS or ASG for 6 weeks. The AS group showed lower levels of amyloid β and beta-site amyloid precursor protein cleaving enzyme 1 expressions and higher expression levels of low-density lipoprotein receptor-related protein 1 than did the control group (p

Original language	English (Ireland)
Pages (from-to)	775-782
Number of pages	8
Journal	Food Science and Biotechnology
Volume	26
Issue number	3
DOIs	https://doi.org/10.1007/s10068-017-0077-3
Publication status	Published - 1 Jun 2017

Keywords

Alzheimer’s disease
Amyloid β
Artemisia scoparia
Oxidative stress
Tau hyperphosphorylation

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10.1007/s10068-017-0077-3

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title = "Artemisia scoparia attenuates amyloid β accumulation and tau hyperphosphorylation in spontaneously hypertensive rats",

abstract = "The preventive effects of Artemisia scoparia extract (AS) and AS + garlic extract (ASG) on the risk of Alzheimer{\textquoteright}s disease (AD) were evaluated in spontaneously hypertensive rats. Rats were supplemented with diets containing 2\% (w/w) of AS or ASG for 6 weeks. The AS group showed lower levels of amyloid β and beta-site amyloid precursor protein cleaving enzyme 1 expressions and higher expression levels of low-density lipoprotein receptor-related protein 1 than did the control group (p ",

keywords = "Alzheimer{\textquoteright}s disease, Amyloid β, Artemisia scoparia, Oxidative stress, Tau hyperphosphorylation",

author = "Kitipong Promyo and Cho, \{Jeong Yong\} and Park, \{Kyung Hee\} and Lily Jaiswal and Park, \{Sun Young\} and Ham, \{Kyung Sik\}",

note = "Publisher Copyright: {\textcopyright} 2017, The Korean Society of Food Science and Technology and Springer Science+Business Media Dordrecht.",

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doi = "10.1007/s10068-017-0077-3",

language = "English (Ireland)",

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T1 - Artemisia scoparia attenuates amyloid β accumulation and tau hyperphosphorylation in spontaneously hypertensive rats

AU - Promyo, Kitipong

AU - Cho, Jeong Yong

AU - Park, Kyung Hee

AU - Jaiswal, Lily

AU - Park, Sun Young

AU - Ham, Kyung Sik

PY - 2017/6/1

Y1 - 2017/6/1

N2 - The preventive effects of Artemisia scoparia extract (AS) and AS + garlic extract (ASG) on the risk of Alzheimer’s disease (AD) were evaluated in spontaneously hypertensive rats. Rats were supplemented with diets containing 2% (w/w) of AS or ASG for 6 weeks. The AS group showed lower levels of amyloid β and beta-site amyloid precursor protein cleaving enzyme 1 expressions and higher expression levels of low-density lipoprotein receptor-related protein 1 than did the control group (p

AB - The preventive effects of Artemisia scoparia extract (AS) and AS + garlic extract (ASG) on the risk of Alzheimer’s disease (AD) were evaluated in spontaneously hypertensive rats. Rats were supplemented with diets containing 2% (w/w) of AS or ASG for 6 weeks. The AS group showed lower levels of amyloid β and beta-site amyloid precursor protein cleaving enzyme 1 expressions and higher expression levels of low-density lipoprotein receptor-related protein 1 than did the control group (p

KW - Alzheimer’s disease

KW - Amyloid β

KW - Artemisia scoparia

KW - Oxidative stress

KW - Tau hyperphosphorylation

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DO - 10.1007/s10068-017-0077-3

M3 - Article

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SP - 775

EP - 782

JO - Food Science and Biotechnology

JF - Food Science and Biotechnology

IS - 3

ER -

Artemisia scoparia attenuates amyloid β accumulation and tau hyperphosphorylation in spontaneously hypertensive rats

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Keywords

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