Atherosclerotic renal artery stenosis and renal artery stenting: An evolving therapeutic option

Ronan Margey, Brian G. Hynes, Darragh Moran, Thomas J. Kiernan, Michael R. Jaff

Research output: Contribution to journalReview articlepeer-review

Abstract

Atherosclerotic renal artery stenosis is a common clinical problem for which the optimal therapeutic strategy remains to be defined. However, renal artery stenting procedures have significantly increased as one approach to treat this clinical problem. Despite improvements in device design and technical performance of the procedure, the benefits and results of randomized clinical trials of renal artery stenting as a therapy remain confusing. Understanding the epidemiology, pathophysiology and natural history of renal artery stenosis are central to improving the outcomes of renal artery stenting. Developing both noninvasive and invasive predictive tools to better identify which patient will respond to renal revascularization will also be beneficial. In this article, we will present an overview of atherosclerotic renal artery disease. The results of renal artery stenting will be discussed and from this, the available noninvasive and invasive tools available to assess the clinical and hemodynamic significance of renal artery stenosis will be presented.

Original languageEnglish
Pages (from-to)1347-1360
Number of pages14
JournalExpert Review of Cardiovascular Therapy
Volume9
Issue number10
DOIs
Publication statusPublished - Oct 2011
Externally publishedYes

Keywords

  • Angioplasty
  • Atheroembolization
  • Atherosclerosis
  • Chronic kidney disease
  • CT angiography
  • Hypertension
  • MR angiography
  • Renal artery stenosis
  • Renal artery stenting
  • Renal duplex ultrasonography
  • Stenting

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