Biophotonics for blood analysis

S. M. Daly

doi:10.1016/B978-0-85709-662-3.00009-9

Biophotonics for blood analysis

S. M. Daly

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

This chapter describes the application of optical methods to blood analysis in an effort to yield qualitative and quantitative metrics pertaining to morphological and functional information. A review of the refractive index matching mechanism of blood optical clearing employing immersion techniques is presented. This concept is discussed on the basis of both in vitro and in vivo studies of a wide variety of optical modalities for the enhancement of light penetration into blood. In addition, the diagnostic and prognostic value of such imaging techniques for dynamic blood flow assessment is presented via comparable descriptions of its invasive predecessors.

Original language	English
Title of host publication	Biophotonics for Medical Applications
Publisher	Elsevier Inc.
Pages	243-299
Number of pages	57
ISBN (Electronic)	9780857096746
ISBN (Print)	9780857096623
DOIs	https://doi.org/10.1016/B978-0-85709-662-3.00009-9
Publication status	Published - 25 Jun 2015

Keywords

Biophotonics
Blood
Flow
Optical imaging
Optical immersion

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10.1016/B978-0-85709-662-3.00009-9

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AB - This chapter describes the application of optical methods to blood analysis in an effort to yield qualitative and quantitative metrics pertaining to morphological and functional information. A review of the refractive index matching mechanism of blood optical clearing employing immersion techniques is presented. This concept is discussed on the basis of both in vitro and in vivo studies of a wide variety of optical modalities for the enhancement of light penetration into blood. In addition, the diagnostic and prognostic value of such imaging techniques for dynamic blood flow assessment is presented via comparable descriptions of its invasive predecessors.

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KW - Blood

KW - Flow

KW - Optical imaging

KW - Optical immersion

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EP - 299

BT - Biophotonics for Medical Applications

PB - Elsevier Inc.

ER -

Biophotonics for blood analysis

Abstract

Keywords

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