Bioprocess intensification: Cases that (don't) work

Luuk A.M. van der Wielen; Solange I. Mussatto; Jan van Breugel

doi:10.1016/j.nbt.2020.11.007

Bioprocess intensification: Cases that (don't) work

Luuk A.M. van der Wielen, Solange I. Mussatto, Jan van Breugel

Department of Chemical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Development of affordable and low carbon biobased manufacturing depends critically on strategies that reduce cost and emission profiles. This paper indicates that efforts around the reduction of capital costs by intensification of process equipment need to be carefully weighed against the inherently fast increasing financial and climate costs of driving forces used for the intensification. The fundamental relation between capital expenditures (CAPEX) and operational expenditures (OPEX) of intensified and non-intensified biobased processes and their financial and climatic impacts are emphasized and provisionally explored for a few industrial processes. General learnings flag the importance in particular of OPEX minimisation for sustainable bio-economic development.

Original language	English
Pages (from-to)	108-115
Number of pages	8
Journal	New Biotechnology
Volume	61
DOIs	https://doi.org/10.1016/j.nbt.2020.11.007
Publication status	Published - 25 Mar 2021

Keywords

Bioprocess intensification
Integrated biobased manufacturing
Techno-Economic assessment
Thermodynamic analysis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.nbt.2020.11.007

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title = "Bioprocess intensification: Cases that (don't) work",

abstract = "Development of affordable and low carbon biobased manufacturing depends critically on strategies that reduce cost and emission profiles. This paper indicates that efforts around the reduction of capital costs by intensification of process equipment need to be carefully weighed against the inherently fast increasing financial and climate costs of driving forces used for the intensification. The fundamental relation between capital expenditures (CAPEX) and operational expenditures (OPEX) of intensified and non-intensified biobased processes and their financial and climatic impacts are emphasized and provisionally explored for a few industrial processes. General learnings flag the importance in particular of OPEX minimisation for sustainable bio-economic development.",

keywords = "Bioprocess intensification, Integrated biobased manufacturing, Techno-Economic assessment, Thermodynamic analysis",

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note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2021",

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AU - van der Wielen, Luuk A.M.

AU - Mussatto, Solange I.

AU - van Breugel, Jan

PY - 2021/3/25

Y1 - 2021/3/25

N2 - Development of affordable and low carbon biobased manufacturing depends critically on strategies that reduce cost and emission profiles. This paper indicates that efforts around the reduction of capital costs by intensification of process equipment need to be carefully weighed against the inherently fast increasing financial and climate costs of driving forces used for the intensification. The fundamental relation between capital expenditures (CAPEX) and operational expenditures (OPEX) of intensified and non-intensified biobased processes and their financial and climatic impacts are emphasized and provisionally explored for a few industrial processes. General learnings flag the importance in particular of OPEX minimisation for sustainable bio-economic development.

AB - Development of affordable and low carbon biobased manufacturing depends critically on strategies that reduce cost and emission profiles. This paper indicates that efforts around the reduction of capital costs by intensification of process equipment need to be carefully weighed against the inherently fast increasing financial and climate costs of driving forces used for the intensification. The fundamental relation between capital expenditures (CAPEX) and operational expenditures (OPEX) of intensified and non-intensified biobased processes and their financial and climatic impacts are emphasized and provisionally explored for a few industrial processes. General learnings flag the importance in particular of OPEX minimisation for sustainable bio-economic development.

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KW - Integrated biobased manufacturing

KW - Techno-Economic assessment

KW - Thermodynamic analysis

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VL - 61

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JO - New Biotechnology

JF - New Biotechnology

ER -

Bioprocess intensification: Cases that (don't) work

Abstract

Keywords

UN SDGs

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