Clinical-grade validation of whole genome sequencing reveals robust detection of low-frequency variants and copy number alterations in CLL

Jenny Klintman, Katerina Barmpouti, Samantha J.L. Knight, Pauline Robbe, Hélène Dreau, Ruth Clifford, Kate Ridout, Adam Burns, Adele Timbs, David Bruce, Pavlos Antoniou, Alona Sosinsky, Jennifer Becq, David Bentley, Peter Hillmen, Jenny C. Taylor, Mark Caulfield, Anna H. Schuh

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Biochemistry, Genetics and Molecular Biology