Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

Paul Murray; Andrew Bell

doi:10.1007/978-3-319-22822-8_12

Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

Paul Murray, Andrew Bell

University of Birmingham

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The morphology of the pathognomonic Hodgkin and Reed-Sternberg cells (HRS) of Hodgkin lymphoma was described over a century ago, yet it was only relatively recently that the B-cell origin of these cells was identified. In a proportion of cases, HRS cells harbour monoclonal forms of the B lymphotropic Epstein- Barr virus (EBV). This review summarises current knowledge of the pathogenesis of Hodgkin lymphoma with a particular emphasis on the contribution of EBV.

Original language	English
Title of host publication	One Herpes Virus
Subtitle of host publication	Many Diseases
Publisher	Springer International Publishing
Pages	287-313
Number of pages	27
Volume	1
ISBN (Electronic)	9783319228228
ISBN (Print)	9783319228211
DOIs	https://doi.org/10.1007/978-3-319-22822-8_12
Publication status	Published - 17 Nov 2015
Externally published	Yes

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10.1007/978-3-319-22822-8_12

Cite this

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Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

Abstract

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