Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

Paul Murray; Andrew Bell

doi:10.1007/978-3-319-22822-8_12

Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

Paul Murray
, Andrew Bell

University of Birmingham

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The morphology of the pathognomonic Hodgkin and Reed-Sternberg cells (HRS) of Hodgkin lymphoma was described over a century ago, yet it was only relatively recently that the B-cell origin of these cells was identified. In a proportion of cases, HRS cells harbour monoclonal forms of the B lymphotropic Epstein-Barr virus (EBV). This review summarises current knowledge of the pathogenesis of Hodgkin lymphoma with a particular emphasis on the contribution of EBV.

Original language	English
Title of host publication	Current Topics in Microbiology and Immunology
Publisher	Springer Verlag
Pages	287-313
Number of pages	27
Volume	1
ISBN (Electronic)	9783319228228
DOIs	https://doi.org/10.1007/978-3-319-22822-8_12
Publication status	Published - 17 Nov 2015
Externally published	Yes

Publication series

Name	Current Topics in Microbiology and Immunology
Volume	390
ISSN (Print)	0070-217X
ISSN (Electronic)	2196-9965

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1007/978-3-319-22822-8_12

Cite this

@inbook{96966a94c70d407c82b8921a65b34c97,

title = "Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma",

abstract = "The morphology of the pathognomonic Hodgkin and Reed-Sternberg cells (HRS) of Hodgkin lymphoma was described over a century ago, yet it was only relatively recently that the B-cell origin of these cells was identified. In a proportion of cases, HRS cells harbour monoclonal forms of the B lymphotropic Epstein-Barr virus (EBV). This review summarises current knowledge of the pathogenesis of Hodgkin lymphoma with a particular emphasis on the contribution of EBV.",

author = "Paul Murray and Andrew Bell",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015",

year = "2015",

month = nov,

day = "17",

doi = "10.1007/978-3-319-22822-8\_12",

language = "English",

volume = "1",

series = "Current Topics in Microbiology and Immunology",

publisher = "Springer Verlag",

pages = "287--313",

booktitle = "Current Topics in Microbiology and Immunology",

}

TY - CHAP

T1 - Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

AU - Murray, Paul

AU - Bell, Andrew

PY - 2015/11/17

Y1 - 2015/11/17

N2 - The morphology of the pathognomonic Hodgkin and Reed-Sternberg cells (HRS) of Hodgkin lymphoma was described over a century ago, yet it was only relatively recently that the B-cell origin of these cells was identified. In a proportion of cases, HRS cells harbour monoclonal forms of the B lymphotropic Epstein-Barr virus (EBV). This review summarises current knowledge of the pathogenesis of Hodgkin lymphoma with a particular emphasis on the contribution of EBV.

AB - The morphology of the pathognomonic Hodgkin and Reed-Sternberg cells (HRS) of Hodgkin lymphoma was described over a century ago, yet it was only relatively recently that the B-cell origin of these cells was identified. In a proportion of cases, HRS cells harbour monoclonal forms of the B lymphotropic Epstein-Barr virus (EBV). This review summarises current knowledge of the pathogenesis of Hodgkin lymphoma with a particular emphasis on the contribution of EBV.

UR - https://www.scopus.com/pages/publications/84942895628

U2 - 10.1007/978-3-319-22822-8_12

DO - 10.1007/978-3-319-22822-8_12

M3 - Chapter

C2 - 26424651

AN - SCOPUS:84942895628

VL - 1

T3 - Current Topics in Microbiology and Immunology

SP - 287

EP - 313

BT - Current Topics in Microbiology and Immunology

PB - Springer Verlag

ER -

Contribution of the epstein-barr virus to the pathogenesis of hodgkin lymphoma

Abstract

Publication series

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this