Controlling polymorphism of p-aminobenzoic acid by sonication

Sandra Gracin, Marketta Uusi-Penttilä, Åke C. Rasmuson

Research output: Contribution to journalArticlepeer-review

Abstract

The influence of ultrasound on the nucleation of p-aminobenzoic acid in supersaturated aqueous solutions has been investigated. The induction time and the solid phase structure has been determined in experiments with and without ultrasound. Different sonication schemes and intensities have been evaluated. It is found that sonication leads to a much shorter and reproducible induction time. In addition, it has been found that sonication preferentially favor the formation of one of the polymorphs.

Original languageEnglish
Article numberC-22
Pages (from-to)677-682
Number of pages6
JournalVDI Berichte
Issue number1901 II
Publication statusPublished - 2005
Externally publishedYes

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