Coronary artery disease and peripheral vascular disease among patients with chronic kidney disease: An epidemiological perspective: An epidemiological perspective

Research output: Contribution to journalArticlepeer-review

Abstract

The enormous burden of CAD and PVD in patients who have CKD contributes substantially to increased morbidity and mortality. The increased risk of vascular disease observed in CKD patients is likely to be multifactorial, with contributions from traditional and nontraditional cardiovascular factors. Given the overwhelming evidence on the known benefits of cardioprotective medications, their underuse remains puzzling in a population at enormous risk. During the past 5 years, the research community and national interest groups have made significant progress in organizing a concerted approach to improve the management of patients who have CKD and vascular disease. Much work remains to be done. The development of national guidelines in the management of these patients at high risk for future cardiovascular events will be a welcome step. The evaluation of multitargeted interventions for reduction of cardiovascular risk through randomized clinical trials is desperately needed. Finally, the low use of known cardioprotective strategies in this high-risk group is a serious issue and warrants immediate attention at local and national levels.

Original languageEnglish (Ireland)
Pages (from-to)285-298
Number of pages14
JournalCardiology Clinics
Volume23
Issue number3
DOIs
Publication statusPublished - Aug 2005

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