TY - JOUR
T1 - Coronary artery perforations in the contemporary interventional era
AU - Kiernan, T. J.
AU - Yan, B. P.
AU - Ruggiero, N.
AU - Eisenberg, J. D.
AU - Bernal, J.
AU - Cubeddu, R. J.
AU - Witzke, C.
AU - Don, C.
AU - Cruz-Gonzalez, I.
AU - Rosenfield, K.
AU - Pomersantev, E.
AU - Palacios, I.
PY - 2009/8
Y1 - 2009/8
N2 - Background: Coronary perforations represent a serious complication of percutaneous coronary intervention (PCI). Methods: We performed a retrospective analysis of documented coronary perforations at Massachusetts General Hospital from 2000 to 2008. Medical records review and detailed angiographic analysis were performed in all patients. Results: Sixty-eight cases of coronary perforation were identified from a total of 14,281 PCIs from March 2000 to March 2008 representing an overall incidence of 0.48%. The study cohort was predominantly male (61.8%), mean age 71±11 years with 78% representing acute cases (unstable angina: 36.8%, NSTEMI: 30.9%, STEMI: 10.3%). Coronary artery perforation occurred as a complication of wire manipulation in 45 patients (66.2%) with 88.9% of this group being hydrophilic wires, of coronary stenting in 11 (16.2%), of angioplasty alone in 6 (8.8%), and of rotational atherectomy in 8 (11.8%). The perforation was sealed with an angioplasty balloon alone in 16 patients (23.5%), and with stents in 14 patients (20.6%) (covered stents: 11.8% and noncovered stents: 8.8%). Emergency CABG was performed in 2 patients (2.9%). Five patients (7.4%) developed periprocedural MI. The in-hospital mortality rate was 5.9% in the study cohort. Conclusion: Coronary artery perforation as a complication of PCI is still rare as demonstrated in our series with an incidence of 0.48%. The predominant cause of coronary perforations in the current era of PCI is wire injury.
AB - Background: Coronary perforations represent a serious complication of percutaneous coronary intervention (PCI). Methods: We performed a retrospective analysis of documented coronary perforations at Massachusetts General Hospital from 2000 to 2008. Medical records review and detailed angiographic analysis were performed in all patients. Results: Sixty-eight cases of coronary perforation were identified from a total of 14,281 PCIs from March 2000 to March 2008 representing an overall incidence of 0.48%. The study cohort was predominantly male (61.8%), mean age 71±11 years with 78% representing acute cases (unstable angina: 36.8%, NSTEMI: 30.9%, STEMI: 10.3%). Coronary artery perforation occurred as a complication of wire manipulation in 45 patients (66.2%) with 88.9% of this group being hydrophilic wires, of coronary stenting in 11 (16.2%), of angioplasty alone in 6 (8.8%), and of rotational atherectomy in 8 (11.8%). The perforation was sealed with an angioplasty balloon alone in 16 patients (23.5%), and with stents in 14 patients (20.6%) (covered stents: 11.8% and noncovered stents: 8.8%). Emergency CABG was performed in 2 patients (2.9%). Five patients (7.4%) developed periprocedural MI. The in-hospital mortality rate was 5.9% in the study cohort. Conclusion: Coronary artery perforation as a complication of PCI is still rare as demonstrated in our series with an incidence of 0.48%. The predominant cause of coronary perforations in the current era of PCI is wire injury.
UR - http://www.scopus.com/inward/record.url?scp=68849088458&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8183.2009.00469.x
DO - 10.1111/j.1540-8183.2009.00469.x
M3 - Article
C2 - 19453819
AN - SCOPUS:68849088458
SN - 0896-4327
VL - 22
SP - 350
EP - 353
JO - Journal of Interventional Cardiology
JF - Journal of Interventional Cardiology
IS - 4
ER -