TY - JOUR
T1 - CO2-Reactive Ionic Liquid Surfactants for the Control of Colloidal Morphology
AU - Brown, Paul
AU - Sresht, Vishnu
AU - Eral, Burak H.
AU - Fiore, Andrew
AU - De La Fuente-Núnez, César
AU - O'Mahony, Marcus
AU - Mendes, Gabriel P.
AU - Heller, William T.
AU - Doyle, Patrick S.
AU - Blankschtein, Daniel
AU - Hatton, T. Alan
N1 - Publisher Copyright:
© 2017 American Chemical Society.
PY - 2017/8/8
Y1 - 2017/8/8
N2 - This article reports on a new class of stimuli-responsive surfactant generated from commercially available amphiphiles such as dodecyltrimethylammmonium bromide (DTAB) by substitution of the halide counterion with counterions such as 2-cyanopyrrolide, 1,2,3-triazolide, and L-proline that complex reversibly with CO2. Through a combination of small-angle neutron scattering (SANS), electrical conductivity measurements, thermal gravimetric analysis, and molecular dynamics simulations, we show how small changes in charge reorganization and counterion shape and size induced by complexation with CO2 allow for fine-tunability of surfactant properties. We then use these findings to demonstrate a range of potential practical uses, from manipulating microemulsion droplet morphology to controlling micellar and vesicular aggregation. In particular, we focus on the binding of these surfactants to DNA and the reversible compaction of surfactant-DNA complexes upon alternate bubbling of the solution with CO2 and N2.
AB - This article reports on a new class of stimuli-responsive surfactant generated from commercially available amphiphiles such as dodecyltrimethylammmonium bromide (DTAB) by substitution of the halide counterion with counterions such as 2-cyanopyrrolide, 1,2,3-triazolide, and L-proline that complex reversibly with CO2. Through a combination of small-angle neutron scattering (SANS), electrical conductivity measurements, thermal gravimetric analysis, and molecular dynamics simulations, we show how small changes in charge reorganization and counterion shape and size induced by complexation with CO2 allow for fine-tunability of surfactant properties. We then use these findings to demonstrate a range of potential practical uses, from manipulating microemulsion droplet morphology to controlling micellar and vesicular aggregation. In particular, we focus on the binding of these surfactants to DNA and the reversible compaction of surfactant-DNA complexes upon alternate bubbling of the solution with CO2 and N2.
UR - http://www.scopus.com/inward/record.url?scp=85027053899&partnerID=8YFLogxK
U2 - 10.1021/acs.langmuir.7b00679
DO - 10.1021/acs.langmuir.7b00679
M3 - Article
C2 - 28699755
AN - SCOPUS:85027053899
SN - 0743-7463
VL - 33
SP - 7633
EP - 7641
JO - Langmuir
JF - Langmuir
IS - 31
ER -