Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients

Peddy Vishweshwar; Jennifer A. McMahon; Matthew L. Peterson; Magali B. Hickey; Tanise R. Shattock; Michael J. Zaworotko

doi:10.1039/b501304f

Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients

Peddy Vishweshwar, Jennifer A. McMahon, Matthew L. Peterson, Magali B. Hickey, Tanise R. Shattock, Michael J. Zaworotko

Research output: Contribution to journal › Article › peer-review

Abstract

The carboxylic acid-primary amide supramolecular heterosynthon is exploited for the generation of pharmaceutical co-crystals that contain two active pharmaceutical ingredients that are polymorphic in their pure forms.

Original language	English
Pages (from-to)	4601-4603
Number of pages	3
Journal	Chemical Communications
Issue number	36
DOIs	https://doi.org/10.1039/b501304f
Publication status	Published - 28 Sep 2005
Externally published	Yes

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title = "Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients",

abstract = "The carboxylic acid-primary amide supramolecular heterosynthon is exploited for the generation of pharmaceutical co-crystals that contain two active pharmaceutical ingredients that are polymorphic in their pure forms.",

author = "Peddy Vishweshwar and McMahon, {Jennifer A.} and Peterson, {Matthew L.} and Hickey, {Magali B.} and Shattock, {Tanise R.} and Zaworotko, {Michael J.}",

year = "2005",

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AU - Vishweshwar, Peddy

AU - McMahon, Jennifer A.

AU - Peterson, Matthew L.

AU - Hickey, Magali B.

AU - Shattock, Tanise R.

AU - Zaworotko, Michael J.

PY - 2005/9/28

Y1 - 2005/9/28

N2 - The carboxylic acid-primary amide supramolecular heterosynthon is exploited for the generation of pharmaceutical co-crystals that contain two active pharmaceutical ingredients that are polymorphic in their pure forms.

AB - The carboxylic acid-primary amide supramolecular heterosynthon is exploited for the generation of pharmaceutical co-crystals that contain two active pharmaceutical ingredients that are polymorphic in their pure forms.

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U2 - 10.1039/b501304f

DO - 10.1039/b501304f

M3 - Article

C2 - 16158128

AN - SCOPUS:26444620704

SN - 1359-7345

SP - 4601

EP - 4603

JO - Chemical Communications

JF - Chemical Communications

IS - 36

ER -

Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients

Abstract

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