Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Lou Ella M.M. Alexander; January Watters; Jessica A. Reusch; Michelle Maurin; Brook S. Nepon-Sixt; Katerina Vrzalikova; Mark G. Alexandrow; Paul G. Murray; Kenneth L. Wright

doi:10.1016/j.dib.2017.09.042

Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Lou Ella M.M. Alexander
, January Watters
, Jessica A. Reusch
, Michelle Maurin
, Brook S. Nepon-Sixt
, Katerina Vrzalikova
, Mark G. Alexandrow
, Paul G. Murray
, Kenneth L. Wright

Research output: Contribution to journal › Article › peer-review

Abstract

The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.

Original language	English
Pages (from-to)	222-227
Number of pages	6
Journal	Data in Brief
Volume	15
DOIs	https://doi.org/10.1016/j.dib.2017.09.042
Publication status	Published - Dec 2017
Externally published	Yes

Keywords

B-cell Lymphoma
Cell division
EBV
ELL3
Transcription elongation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.dib.2017.09.042

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@article{4a3362c927cb4d3aae5a58f572615042,

title = "Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells",

abstract = "The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.",

keywords = "B-cell Lymphoma, Cell division, EBV, ELL3, Transcription elongation",

author = "Alexander, \{Lou Ella M.M.\} and January Watters and Reusch, \{Jessica A.\} and Michelle Maurin and Nepon-Sixt, \{Brook S.\} and Katerina Vrzalikova and Alexandrow, \{Mark G.\} and Murray, \{Paul G.\} and Wright, \{Kenneth L.\}",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

month = dec,

doi = "10.1016/j.dib.2017.09.042",

language = "English",

volume = "15",

pages = "222--227",

journal = "Data in Brief",

issn = "2352-3409",

}

TY - JOUR

T1 - Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

AU - Alexander, Lou Ella M.M.

AU - Watters, January

AU - Reusch, Jessica A.

AU - Maurin, Michelle

AU - Nepon-Sixt, Brook S.

AU - Vrzalikova, Katerina

AU - Alexandrow, Mark G.

AU - Murray, Paul G.

AU - Wright, Kenneth L.

PY - 2017/12

Y1 - 2017/12

N2 - The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.

AB - The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival” (Alexander et al., 2017) [1]. The cited research article characterizes Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) expression in the B cell compartment and functional dependence in B lymphoma cell lines. This data report describes the mRNA expression pattern in a panel of cell lines representing the B cell compartment, supplementing the protein expression data presented in the associated research report. In addition, a reanalysis is presented of publicly available mRNA expression data from primary murine B cells to reveal dynamic regulation of the ELL family members post LPS stimulation (Barwick et al., 2016) [2]. The effect of ELL3 depletion on cell morphology, latent Epstein Barr Virus (EBV) lytic replication and differentiation markers in a Burkitt's lymphoma (BL) cell line cells are presented.

KW - B-cell Lymphoma

KW - Cell division

KW - EBV

KW - ELL3

KW - Transcription elongation

UR - https://www.scopus.com/pages/publications/85030702041

U2 - 10.1016/j.dib.2017.09.042

DO - 10.1016/j.dib.2017.09.042

M3 - Article

AN - SCOPUS:85030702041

SN - 2352-3409

VL - 15

SP - 222

EP - 227

JO - Data in Brief

JF - Data in Brief

ER -

Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells

Abstract

Keywords

UN SDGs

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