TY - JOUR
T1 - Detecting molecular vibrational modes of side chains and endpoints in nanoscale proteins with graphene plasmon
AU - Wu, Chenchen
AU - Liu, Ning
AU - Hu, Hai
AU - Guo, Xiangdong
AU - Liao, Baoxin
AU - Liu, Jiaming
AU - Wang, Liming
AU - Chen, Chunying
AU - Yang, Xiaoxia
AU - Dai, Qing
N1 - Publisher Copyright:
© 2019 Chinese Optics Letters.
PY - 2019/6/10
Y1 - 2019/6/10
N2 - Monitoring the chemical and structural changes in protein side chains and endpoints by infrared (IR) spectroscopy is important for studying the chemical reaction and physical adsorption process of proteins. However, the detection of side chains and endpoints in nanoscale proteins is still challenging due to its weak IR response. Here, by designing a double layered graphene plasmon sensor on MgF2/Si substrate in the IR fingerprint region, we detect the vibrational modes in side chains and endpoints (1397 cm-1 and 1458 cm-1) of monolayer protein. The sensor could be applied on biochemistry to investigate the physical and chemical reaction of biomolecules.
AB - Monitoring the chemical and structural changes in protein side chains and endpoints by infrared (IR) spectroscopy is important for studying the chemical reaction and physical adsorption process of proteins. However, the detection of side chains and endpoints in nanoscale proteins is still challenging due to its weak IR response. Here, by designing a double layered graphene plasmon sensor on MgF2/Si substrate in the IR fingerprint region, we detect the vibrational modes in side chains and endpoints (1397 cm-1 and 1458 cm-1) of monolayer protein. The sensor could be applied on biochemistry to investigate the physical and chemical reaction of biomolecules.
UR - http://www.scopus.com/inward/record.url?scp=85069805442&partnerID=8YFLogxK
U2 - 10.3788/COL201917.062401
DO - 10.3788/COL201917.062401
M3 - Article
AN - SCOPUS:85069805442
SN - 1671-7694
VL - 17
JO - Chinese Optics Letters
JF - Chinese Optics Letters
IS - 6
M1 - 062401
ER -