Development of mesenteric tissues

Kevin Gerard Byrnes, Kieran McDermott, John Calvin Coffey

Research output: Contribution to journalReview articlepeer-review

Abstract

Mesothelial, neurovascular, lymphatic, adipose and mesenchymal tissues make up the mesentery. These tissues are pathobiologically important for numerous reasons. Collectively, they form a continuous, discrete and substantive organ. Additionally, they maintain abdominal digestive organs in position and in continuity with other systems. Furthermore, as they occupy a central position, they mediate transmission of signals between the abdominal digestive system and the remainder of the body. Despite this physiologic centrality, mesenteric tissue development has received little investigatory focus. However, recent advances in our understanding of anatomy demonstrate continuity between all mesenteric tissues, thereby linking previously unrelated studies. In this review, we examine the development of mesenteric tissue in normality and in the setting of congenital abnormalities.

Original languageEnglish
Pages (from-to)55-62
Number of pages8
JournalSeminars in Cell and Developmental Biology
Volume92
DOIs
Publication statusPublished - Aug 2019

Keywords

  • Development
  • Embryology
  • Mesentery
  • Organogenesis
  • Tissue

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