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Diagnostic domains, differential diagnosis and conditions requiring further medical attention that are considered important in the assessment for Achilles tendinopathy: a Delphi consensus study

  • Peter Malliaras
    • Faculty of Medicine, Nursing and Health Sciences, Monash University
    • University of Delaware
    • Erasmus Medical Center, Rotterdam
    • University of Deusto Faculty of Health Sciences
    • California State University Chico
    • Copenhagen University Hospital-Bispebjerg and Frederiksberg Institute of Sports Medicine Copenhagen
    • Norwegian School of Sport Sciences
    • Esporte Clube Bahia
    • Aspetar Orthopedic and Sports Medicine Hospital
    • University of Gothenburg Sahlgrenska Academy
    • Queen Mary University of London Wolfson Institute of Population Health
    • Alphington Sports Medicine
    • Olympic Park Sports Medicine Centre
    • University of Iowa
    • University of Southampton School of Health Sciences
    • Aspetar Orthopaedic and Sports Hospital
    • Stellenbosch University Faculty of Medicine and Health Sciences
    • United States Olympic and Paralympic Committee
    • Hong Kong Polytechnic University
    • Leeds Community Healthcare NHS Trust
    • Auckland University of Technology
    • Sahlgrenska University Hospital
    • Copenhagen University Hospital
    • Fortius Clinic
    • Podiatry
    • University of Southern California
    • Institute of Sport Exercise and Health
    • Chinese University of Hong Kong
    • University of Rome La Sapienza Faculty of Medicine and Psychology
    • La Trobe University La Trobe Sport and Exercise Medicine Research Centre
    • Physiotherapy Department
    • Rheumatology Department
    • Queen Mary University of London
    • La Trobe University School of Allied Health
    • Edith Cowan University
    • University of Leicester
    • Barts and The London School of Medicine and Dentistry
    • Stanford Hall Defence Medical Rehabilitation Centre
    • La Trobe University
    • Universidad Nacional de Cordoba
    • The University of British Columbia - Vancouver Campus
    • One Welbeck Surgery Centre
    • Huashan Hospital Fudan University Department of Sports Medicine
    • Department of Orthopedics and Sports Medicine

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The absence of agreed methods to diagnose Achilles tendinopathy impedes research and clinical practice. This gap results in heterogeneous and/or poorly described study samples, making it challenging to apply findings in clinical practice. The aim of this Delphi study was to define consensus on (1) diagnostic domains; (2) differential diagnoses; and (3) conditions requiring further medical attention, when assessing for Achilles tendinopathy. We conducted a sequential three-stage process which included: (1) identifying diagnostic domains, differential diagnoses and conditions requiring further medical attention based on existing scoping reviews and clinical practice guidelines; (2) developing Delphi survey questions; and (3) administering a five-round Delphi online survey. Consensus was defined as ≥70% agreement. 52 participants completed the surveys. Four diagnostic domains were deemed essential and reached consensus (pain location (93%); pain during activity (97%); tests that provoke pain (87%); palpation to assess pain (83%)). 15 differential diagnoses reached consensus: 2 for both midportion and insertional (partial tear (80%); posterior ankle impingement (78%)), 6 for midportion (plantaris tendinopathy (84%); tibialis posterior or flexor hallucis longus tendinopathy/tenosynovitis (72%); flexor digitorum longus tendinopathy (77%); accessory soleus muscle (74%); paratendinopathy (86%); sural nerve neuropathy (81%)) and 7 for insertional (superficial (88%) and retrocalcaneal bursitis (86%); Haglund's/calcaneal exostosis (80%), intratendinous calcifications (73%); Sever's disease (78%); calcaneal stress reaction/fracture (80%); subtalar/ankle pain (71%)). Six conditions requiring further medical attention reached consensus: (Achilles tendon rupture (83%); systemic inflammatory joint disease (86%); metabolic syndrome (75%); familial hypercholesterolaemia (77%); endocrine and hormonal disorders (80%); drug reactions (77%)). This consensus identified essential diagnostic domains, differential diagnoses and conditions requiring further medical attention that should be considered when assessing for Achilles tendinopathy.

    Original languageEnglish
    Article number9185
    Pages (from-to)891-901
    Number of pages11
    JournalBritish Journal of Sports Medicine
    Volume59
    Issue number13
    Early online date16 Apr 2025
    DOIs
    Publication statusPublished - 1 Jul 2025

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