TY - JOUR
T1 - Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study
AU - Gulseth, Hanne L.
AU - Gjelstad, Ingrid M.F.
AU - Tierney, Audrey C.
AU - Shaw, Danielle I.
AU - Helal, Olfa
AU - Hees, Anneke M.J.V.
AU - Delgado-Lista, Javier
AU - Leszczynska-Golabek, Iwona
AU - Karlström, Brita
AU - Lovegrove, Julie
AU - Defoort, Catherine
AU - Blaak, Ellen E.
AU - Lopez-Miranda, Jose
AU - Dembinska-Kiec, Aldona
AU - Risérus, Ulf
AU - Roche, Helen M.
AU - Birkeland, Kåre I.
AU - Drevon, Christian A.
PY - 2010/7
Y1 - 2010/7
N2 - Hypertension is a key feature of the metabolic syndrome. Lifestyle and dietary changes may affect blood pressure (BP), but the knowledge of the effects of dietary fat modification in subjects with the metabolic syndrome is limited. The objective of the present study was to investigate the effect of an isoenergetic change in the quantity and quality of dietary fat on BP in subjects with the metabolic syndrome. In a 12-week European multi-centre, parallel, randomised controlled dietary intervention trial (LIPGENE), 486 subjects were assigned to one of the four diets distinct in fat quantity and quality: two high-fat diets rich in saturated fat or monounsaturated fat and two low-fat, high-complex carbohydrate diets with or without 12g/d of very long-chain n-3 PUFA supplementation. There were no overall differences in systolic BP (SBP), diastolic BP or pulse pressure (PP) between the dietary groups after the intervention. The high-fat diet rich in saturated fat had minor unfavourable effects on SBP and PP in males.
AB - Hypertension is a key feature of the metabolic syndrome. Lifestyle and dietary changes may affect blood pressure (BP), but the knowledge of the effects of dietary fat modification in subjects with the metabolic syndrome is limited. The objective of the present study was to investigate the effect of an isoenergetic change in the quantity and quality of dietary fat on BP in subjects with the metabolic syndrome. In a 12-week European multi-centre, parallel, randomised controlled dietary intervention trial (LIPGENE), 486 subjects were assigned to one of the four diets distinct in fat quantity and quality: two high-fat diets rich in saturated fat or monounsaturated fat and two low-fat, high-complex carbohydrate diets with or without 12g/d of very long-chain n-3 PUFA supplementation. There were no overall differences in systolic BP (SBP), diastolic BP or pulse pressure (PP) between the dietary groups after the intervention. The high-fat diet rich in saturated fat had minor unfavourable effects on SBP and PP in males.
KW - Blood pressure
KW - Diet
KW - Fatty acids
KW - LIPGENE
KW - Metabolic syndrome
UR - http://www.scopus.com/inward/record.url?scp=77955285100&partnerID=8YFLogxK
U2 - 10.1017/S0007114510000565
DO - 10.1017/S0007114510000565
M3 - Article
C2 - 20202290
AN - SCOPUS:77955285100
SN - 0007-1145
VL - 104
SP - 160
EP - 163
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 2
ER -