Abstract
Indirect treatment comparisons are useful to estimate relative treatment effects when head-to-head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost-effectiveness of new medicines as part of multidisciplinary teams. We describe some shared observations on areas where reporting of population-adjustment indirect comparison methods is causing uncertainty in our recommendations to decision-making committees when assessing reimbursement of medicines.
Original language | English |
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Pages (from-to) | 615-617 |
Number of pages | 3 |
Journal | Research Synthesis Methods |
Volume | 10 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Dec 2019 |
Keywords
- decision making
- evidence synthesis
- population-adjusted indirect comparisons
- statistical models