TY - JOUR
T1 - Evaluation of the in vitro anti-atherogenic properties of lipid fractions of olive pomace, olive pomace enriched fish feed and gilthead sea bream (sparus aurata) fed with olive pomace enriched fish feed
AU - Nasopoulou, Constantina
AU - Gogaki, Vassiliki
AU - Stamatakis, Giorgos
AU - Papaharisis, Leonidas
AU - Demopoulos, Constantinos A.
AU - Zabetakis, Ioannis
PY - 2013/10
Y1 - 2013/10
N2 - Given the pivotal role of Platelet-Activating-Factor (PAF) in atherosclerosis and the cardio-protective role of PAF-inhibitors derived from olive pomace, the inclusion of olive pomace in fish feed has been studied for gilthead sea bream (Sparus aurata). The aim of the current research was to elucidate the anti-atherogenic properties of specific HPLC lipid fractions obtained from olive pomace, olive pomace enriched fish feed and fish fed with the olive pomace enriched fish feed, by evaluating their in vitro biological activity against washed rabbit platelets. This in vitro study underlines that olive pomace inclusion in fish feed improves the nutritional value of both fish feed and fish possibly by enriching the marine lipid profile of gilthead sea bream (Sparus aurata) with specific bioactive lipid compounds of plant origin.
AB - Given the pivotal role of Platelet-Activating-Factor (PAF) in atherosclerosis and the cardio-protective role of PAF-inhibitors derived from olive pomace, the inclusion of olive pomace in fish feed has been studied for gilthead sea bream (Sparus aurata). The aim of the current research was to elucidate the anti-atherogenic properties of specific HPLC lipid fractions obtained from olive pomace, olive pomace enriched fish feed and fish fed with the olive pomace enriched fish feed, by evaluating their in vitro biological activity against washed rabbit platelets. This in vitro study underlines that olive pomace inclusion in fish feed improves the nutritional value of both fish feed and fish possibly by enriching the marine lipid profile of gilthead sea bream (Sparus aurata) with specific bioactive lipid compounds of plant origin.
KW - Anti-atherogenic properties
KW - Gilthead sea bream (Sparus aurata)
KW - HPLC
KW - Olive pomace
KW - Platelet activating factor
UR - https://www.scopus.com/pages/publications/84887056595
U2 - 10.3390/md11103676
DO - 10.3390/md11103676
M3 - Article
C2 - 24084786
AN - SCOPUS:84887056595
SN - 1660-3397
VL - 11
SP - 3676
EP - 3688
JO - Marine Drugs
JF - Marine Drugs
IS - 10
ER -