Abstract
Serum prolactin (PRL) was used as a hormone marker of serotoninergic function following oral administration of an acute dose of a serotoninergic agonist. Five male endurance‐trained athletes (ET) and five healthy non‐endurance‐trained controls (NT) were studied. The peak PRL concentration was lower (P = 0.031) for the ET athletes (486 +/‐ 208 mU l‐1; mean +/‐ S.D.) than for the NT controls (1000 +/‐ 385 mU l‐1); the total release of PRL was also lower (P = 0.042) for the ET subjects. The lower neuroendocrine response to a serotoninergic agonist in the endurance‐trained athletes suggests a downregulation of central serotoninergic receptor function in response to endurance training in man.
Original language | English (Ireland) |
---|---|
Pages (from-to) | 461-464 |
Number of pages | 4 |
Journal | Experimental Physiology |
Volume | 79 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 May 1994 |