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Expansion and differentiation of ex vivo cultured erythroblasts in scalable stirred bioreactors
Joan Sebastián Gallego-Murillo
, Giulia Iacono
,
Luuk A.M. van der Wielen
, Emile van den Akker
, Marieke von Lindern
, Sebastian Aljoscha Wahl
Department of Chemical Sciences
Sanquin Blood Supply Foundation
Delft University of Technology
Meatable
Friedrich-Alexander University Erlangen-Nürnberg
Research output
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peer-review
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Biochemistry, Genetics and Molecular Biology
Oxygen Concentration
100%
Dynamics
50%
Oxygen Consumption
50%
Scale up
50%
Erythrocyte Culture
50%
Large Scale Production
50%
Sparging
50%
Engineering
Erythrocyte
100%
Bioreactor
100%
Dissolved Oxygen Concentration
50%
Transients
25%
Static Condition
25%
Negative Impact
25%
Stirred-Tank Bioreactors
25%
Setpoints
25%
Mass Production
25%
Immunology and Microbiology
Erythroblast
100%
Bioreactor
100%
Oxygen Concentration
33%
Dynamics
16%
Erythrocyte
16%
Oxygen Consumption
16%
Erythrocyte Culture
16%
Scale up
16%
Large Scale Production
16%
Sparging
16%
Hemoglobin
16%
Medicine and Dentistry
Erythroblast
100%
Ex Vivo
100%
Erythrocyte
50%
Dissolved Oxygen
33%
Oxygen Consumption
16%
Erythrocyte Culture
16%
Cell Therapy
16%
Enucleation
16%
Chemical Engineering
Dissolved Oxygen
100%
Biochemical Reactor
100%
Stirred Reactor
100%
Sparging
50%