Exploring the advantages of PAT for pharmaceutical cleaning in Ireland

Process analytical technology (PAT) and its applications have been used in various industrial processes for a long time. It originates from the last century where its first application was in Germany after World War II within the chemical and petrochemical industry¹. Following this, it was implemented and refined in different industries worldwide - for example in refineries and petrochemical plants - until it became an integral part of process control. However, it is considered a young technology in pharmaceutical manufacturing where the processes have always been restricted to conventional approaches. This forces many limitations on product quality monitoring since the control relies mainly on collected samples being tested off-line in a laboratory.