TY - JOUR
T1 - From the forest to the plate – Hemicelluloses, galactoglucomannan, glucuronoxylan, and phenolic-rich extracts from unconventional sources as functional food ingredients
AU - Granato, Daniel
AU - Reshamwala, Dhanik
AU - Korpinen, Risto
AU - Azevedo, Luciana
AU - Vieira do Carmo, Mariana Araújo
AU - Cruz, Thiago Mendanha
AU - Marques, Mariza Boscacci
AU - Wen, Mingchun
AU - Zhang, Liang
AU - Marjomäki, Varpu
AU - Kilpeläinen, Petri
N1 - Publisher Copyright:
© 2022 The Author(s)
PY - 2022/7/1
Y1 - 2022/7/1
N2 - This study aimed to characterise pressurised hot water (PHW) extracts from nonconventional sources of functional carbohydrates and phenolic compounds in terms of antioxidant capacity, antiviral activity, toxicity, and human erythrocytes’ protection antidiabetic potential. PHW extracts of Norway spruce bark (E1 + E2) and Birch sawdust (E3 + E4) contained mostly galactoglucomannan and glucuronoxylan. In contrast, samples E5 to E9 PHW extracted from Norway spruce, and Scots pine bark are rich sources of phenolic compounds. Overall, phenolic-rich extracts presented the highest inhibition of α-amylase and α-glucosidase and protection against stable non-enveloped enteroviruses. Additionally, all extracts protected human erythrocytes from hemolysis. Cell-based experiments using human cell lines (IMR90 and A549) showed extracts’ non-toxic in vitro profile. Considering the relative toxicological safety of extracts from these unconventional sources, functional carbohydrates and polyphenol-rich extracts can be obtained and further used in food models.
AB - This study aimed to characterise pressurised hot water (PHW) extracts from nonconventional sources of functional carbohydrates and phenolic compounds in terms of antioxidant capacity, antiviral activity, toxicity, and human erythrocytes’ protection antidiabetic potential. PHW extracts of Norway spruce bark (E1 + E2) and Birch sawdust (E3 + E4) contained mostly galactoglucomannan and glucuronoxylan. In contrast, samples E5 to E9 PHW extracted from Norway spruce, and Scots pine bark are rich sources of phenolic compounds. Overall, phenolic-rich extracts presented the highest inhibition of α-amylase and α-glucosidase and protection against stable non-enveloped enteroviruses. Additionally, all extracts protected human erythrocytes from hemolysis. Cell-based experiments using human cell lines (IMR90 and A549) showed extracts’ non-toxic in vitro profile. Considering the relative toxicological safety of extracts from these unconventional sources, functional carbohydrates and polyphenol-rich extracts can be obtained and further used in food models.
KW - Cell-based models
KW - Forest byproducts
KW - Galactoglucomannans
KW - Phenolic composition
KW - Reactive oxygen species
KW - Tannins
UR - http://www.scopus.com/inward/record.url?scp=85123833009&partnerID=8YFLogxK
U2 - 10.1016/j.foodchem.2022.132284
DO - 10.1016/j.foodchem.2022.132284
M3 - Article
C2 - 35121317
AN - SCOPUS:85123833009
SN - 0308-8146
VL - 381
SP - 132284
JO - Food Chemistry
JF - Food Chemistry
M1 - 132284
ER -