Hyaluronic acid association with bacterial, fungal and viral infections: Can hyaluronic acid be used as an antimicrobial polymer for biomedical and pharmaceutical applications?

Fernanda Zamboni; Chun Kwok Wong; Maurice N. Collins

doi:10.1016/j.bioactmat.2022.04.023

Hyaluronic acid association with bacterial, fungal and viral infections: Can hyaluronic acid be used as an antimicrobial polymer for biomedical and pharmaceutical applications?

Fernanda Zamboni, Chun Kwok Wong, Maurice N. Collins

Research output: Contribution to journal › Review article › peer-review

Abstract

The relationships between hyaluronic acid (HA) and pathological microorganisms incite new understandings on microbial infection, tissue penetration, disease progression and lastly, potential treatments. These understandings are important for the advancement of next generation antimicrobial therapeutical strategies for the control of healthcare-associated infections. Herein, this review will focus on the interplay between HA, bacteria, fungi, and viruses. This review will also comprehensively detail and discuss the antimicrobial activity displayed by various HA molecular weights for a variety of biomedical and pharmaceutical applications, including microbiology, pharmaceutics, and tissue engineering.

Original language	English
Pages (from-to)	458-473
Number of pages	16
Journal	Bioactive Materials
Volume	19
DOIs	https://doi.org/10.1016/j.bioactmat.2022.04.023
Publication status	Published - Jan 2023

Keywords

Antibacterial
Antifungal
Antiviral
Hyaluronic acid
Hyaluronidase
Virulence

Access to Document

10.1016/j.bioactmat.2022.04.023

Cite this

@article{2bbac77a159042c4b498ac45353c807d,

title = "Hyaluronic acid association with bacterial, fungal and viral infections: Can hyaluronic acid be used as an antimicrobial polymer for biomedical and pharmaceutical applications?",

abstract = "The relationships between hyaluronic acid (HA) and pathological microorganisms incite new understandings on microbial infection, tissue penetration, disease progression and lastly, potential treatments. These understandings are important for the advancement of next generation antimicrobial therapeutical strategies for the control of healthcare-associated infections. Herein, this review will focus on the interplay between HA, bacteria, fungi, and viruses. This review will also comprehensively detail and discuss the antimicrobial activity displayed by various HA molecular weights for a variety of biomedical and pharmaceutical applications, including microbiology, pharmaceutics, and tissue engineering.",

keywords = "Antibacterial, Antifungal, Antiviral, Hyaluronic acid, Hyaluronidase, Virulence",

author = "Fernanda Zamboni and Wong, {Chun Kwok} and Collins, {Maurice N.}",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2023",

month = jan,

doi = "10.1016/j.bioactmat.2022.04.023",

language = "English",

volume = "19",

pages = "458--473",

journal = "Bioactive Materials",

issn = "2452-199X",

}

TY - JOUR

T1 - Hyaluronic acid association with bacterial, fungal and viral infections

T2 - Can hyaluronic acid be used as an antimicrobial polymer for biomedical and pharmaceutical applications?

AU - Zamboni, Fernanda

AU - Wong, Chun Kwok

AU - Collins, Maurice N.

PY - 2023/1

Y1 - 2023/1

N2 - The relationships between hyaluronic acid (HA) and pathological microorganisms incite new understandings on microbial infection, tissue penetration, disease progression and lastly, potential treatments. These understandings are important for the advancement of next generation antimicrobial therapeutical strategies for the control of healthcare-associated infections. Herein, this review will focus on the interplay between HA, bacteria, fungi, and viruses. This review will also comprehensively detail and discuss the antimicrobial activity displayed by various HA molecular weights for a variety of biomedical and pharmaceutical applications, including microbiology, pharmaceutics, and tissue engineering.

AB - The relationships between hyaluronic acid (HA) and pathological microorganisms incite new understandings on microbial infection, tissue penetration, disease progression and lastly, potential treatments. These understandings are important for the advancement of next generation antimicrobial therapeutical strategies for the control of healthcare-associated infections. Herein, this review will focus on the interplay between HA, bacteria, fungi, and viruses. This review will also comprehensively detail and discuss the antimicrobial activity displayed by various HA molecular weights for a variety of biomedical and pharmaceutical applications, including microbiology, pharmaceutics, and tissue engineering.

KW - Antibacterial

KW - Antifungal

KW - Antiviral

KW - Hyaluronic acid

KW - Hyaluronidase

KW - Virulence

UR - http://www.scopus.com/inward/record.url?scp=85129270407&partnerID=8YFLogxK

U2 - 10.1016/j.bioactmat.2022.04.023

DO - 10.1016/j.bioactmat.2022.04.023

M3 - Review article

AN - SCOPUS:85129270407

SN - 2452-199X

VL - 19

SP - 458

EP - 473

JO - Bioactive Materials

JF - Bioactive Materials

ER -

Hyaluronic acid association with bacterial, fungal and viral infections: Can hyaluronic acid be used as an antimicrobial polymer for biomedical and pharmaceutical applications?

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this