Hydrogel functionalization and crosslinking strategies for biomedical applications

Maurice N. Collins; Lorna Cagney; A. V. Thanusha

doi:10.1016/B978-0-12-823948-3.00007-5

Hydrogel functionalization and crosslinking strategies for biomedical applications

Maurice N. Collins, Lorna Cagney, A. V. Thanusha

University of Limerick

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Hydrogels are three-dimensional crosslinked hydrophilic polymeric network that has attracted considerable attention due to their water-absorbing capacity and swell to simulate biological tissue. Based on source and characteristics, hydrogels can be broadly categorized as natural, synthetic, or hybrids of both. Naturally derived hydrogels exhibit biocompatibility, biodegradability, and ease of processing. While synthetic hydrogels possess mechanical strength, the main aim of this chapter is to summarize the latest chemistries and functionalization strategies for the most common natural and synthetic hydrogels for medical application.

Original language	English
Title of host publication	Hydrogels for Tissue Engineering and Regenerative Medicine
Subtitle of host publication	From Fundamentals to Applications
Publisher	Elsevier
Pages	105-137
Number of pages	33
ISBN (Electronic)	9780128239483
ISBN (Print)	9780128242254
DOIs	https://doi.org/10.1016/B978-0-12-823948-3.00007-5
Publication status	Published - 1 Jan 2023

Keywords

PVA
Synthetic polymers
agarose
alginate
cellulose
chitosan
collagen
crosslinking
elastin
gellan gum
hyaluronic acid
hydrogel
medical applications
molecular structure
natural polymers
polyacrylamide
polyethylene glycol
polymers
silk fibroin

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10.1016/B978-0-12-823948-3.00007-5

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title = "Hydrogel functionalization and crosslinking strategies for biomedical applications",

abstract = "Hydrogels are three-dimensional crosslinked hydrophilic polymeric network that has attracted considerable attention due to their water-absorbing capacity and swell to simulate biological tissue. Based on source and characteristics, hydrogels can be broadly categorized as natural, synthetic, or hybrids of both. Naturally derived hydrogels exhibit biocompatibility, biodegradability, and ease of processing. While synthetic hydrogels possess mechanical strength, the main aim of this chapter is to summarize the latest chemistries and functionalization strategies for the most common natural and synthetic hydrogels for medical application.",

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T1 - Hydrogel functionalization and crosslinking strategies for biomedical applications

AU - Collins, Maurice N.

AU - Cagney, Lorna

AU - Thanusha, A. V.

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N2 - Hydrogels are three-dimensional crosslinked hydrophilic polymeric network that has attracted considerable attention due to their water-absorbing capacity and swell to simulate biological tissue. Based on source and characteristics, hydrogels can be broadly categorized as natural, synthetic, or hybrids of both. Naturally derived hydrogels exhibit biocompatibility, biodegradability, and ease of processing. While synthetic hydrogels possess mechanical strength, the main aim of this chapter is to summarize the latest chemistries and functionalization strategies for the most common natural and synthetic hydrogels for medical application.

AB - Hydrogels are three-dimensional crosslinked hydrophilic polymeric network that has attracted considerable attention due to their water-absorbing capacity and swell to simulate biological tissue. Based on source and characteristics, hydrogels can be broadly categorized as natural, synthetic, or hybrids of both. Naturally derived hydrogels exhibit biocompatibility, biodegradability, and ease of processing. While synthetic hydrogels possess mechanical strength, the main aim of this chapter is to summarize the latest chemistries and functionalization strategies for the most common natural and synthetic hydrogels for medical application.

KW - PVA

KW - Synthetic polymers

KW - agarose

KW - alginate

KW - cellulose

KW - chitosan

KW - collagen

KW - crosslinking

KW - elastin

KW - gellan gum

KW - hyaluronic acid

KW - hydrogel

KW - medical applications

KW - molecular structure

KW - natural polymers

KW - polyacrylamide

KW - polyethylene glycol

KW - polymers

KW - silk fibroin

UR - https://www.scopus.com/pages/publications/85176820424

U2 - 10.1016/B978-0-12-823948-3.00007-5

DO - 10.1016/B978-0-12-823948-3.00007-5

M3 - Chapter

AN - SCOPUS:85176820424

SN - 9780128242254

SP - 105

EP - 137

BT - Hydrogels for Tissue Engineering and Regenerative Medicine

PB - Elsevier

ER -

Hydrogel functionalization and crosslinking strategies for biomedical applications

Abstract

Keywords

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