TY - JOUR
T1 - Identification of high-value bioactive constituents in Northern European willow varieties
T2 - S.X. Dasyclados, Endeavour, Cheviot, Tora, Resolution, S. Purpurea, Terranova, endurance
AU - Hijazi, Ayman
AU - Pisano’, Italo
AU - Leahy, J. J.
AU - Kwapinski, Witold
AU - Johnston, Christopher R.
AU - Prendergast, John
N1 - Publisher Copyright:
© 2022 The Author(s)
PY - 2022/11
Y1 - 2022/11
N2 - Willow trees have maintained their place in medicine for many years as they are herbal source of various cures. Willow varieties are considered to contain a wide range of anti-inflammatory and anti-bacterial species such as salicylates and flavonoids. The current work is centred on the presence of high bioactive pharmaceutical constituents other than salicin such as flavan-3-ol catechin, salicortin, and other complex compounds, which contribute to the total medical value of willow extracts. To evaluate the distribution of these bioactives, bark, and wood fractions of 8 different willow varieties (S.X. Dasyclados, Endeavour, Cheviot, Tora, Resolution, S. Purpurea, Terranova, Endurance) were extracted using dispersive solid phase extraction and then analysed using LC-MS comprising a quadrupole time-of-flight spectrometer. Indeed, various high value constituents such as salicortin, catechin, triandrin, acacetin-5-O-xyloside, picein, apigenin-7-O-glucoside, vitexin-2-rhamnoside, luteolin-7-glucoside, catechin gallate, and kaempferol as well as giberellic and 5-methoxysalicylic acid were detected in bark and wood fractions of the willow varieties 80:20 ethanol/water extracts.
AB - Willow trees have maintained their place in medicine for many years as they are herbal source of various cures. Willow varieties are considered to contain a wide range of anti-inflammatory and anti-bacterial species such as salicylates and flavonoids. The current work is centred on the presence of high bioactive pharmaceutical constituents other than salicin such as flavan-3-ol catechin, salicortin, and other complex compounds, which contribute to the total medical value of willow extracts. To evaluate the distribution of these bioactives, bark, and wood fractions of 8 different willow varieties (S.X. Dasyclados, Endeavour, Cheviot, Tora, Resolution, S. Purpurea, Terranova, Endurance) were extracted using dispersive solid phase extraction and then analysed using LC-MS comprising a quadrupole time-of-flight spectrometer. Indeed, various high value constituents such as salicortin, catechin, triandrin, acacetin-5-O-xyloside, picein, apigenin-7-O-glucoside, vitexin-2-rhamnoside, luteolin-7-glucoside, catechin gallate, and kaempferol as well as giberellic and 5-methoxysalicylic acid were detected in bark and wood fractions of the willow varieties 80:20 ethanol/water extracts.
KW - Anti-inflammatory
KW - Bark
KW - Bioactives
KW - Polyphenols
KW - Salicin
KW - Willow
UR - http://www.scopus.com/inward/record.url?scp=85138173804&partnerID=8YFLogxK
U2 - 10.1016/j.phyplu.2022.100342
DO - 10.1016/j.phyplu.2022.100342
M3 - Article
AN - SCOPUS:85138173804
SN - 2667-0313
VL - 2
JO - Phytomedicine Plus
JF - Phytomedicine Plus
IS - 4
M1 - 100342
ER -