In vitro response of osteoblast-like cells to hydroxyapatite-zinc oxide polyacrylic acid cements

J Tony Pembroke; S. Kenny; M. Buggy; R. Hill; P. V. Hatton

In vitro response of osteoblast-like cells to hydroxyapatite-zinc oxide polyacrylic acid cements

J Tony Pembroke, S. Kenny, M. Buggy, R. Hill, P. V. Hatton

Retired Staff

University of Limerick

Research output: Contribution to journal › Article › peer-review

Abstract

The responses of an osteoblast-like cell line to hydroxyapatite-zinc oxide-polyalkonate cement composites were investigated. The experiments demonstrated that zinc-based cements were cytotoxic in vitro under certain conditions. The setting of these cements involved neutralisation of acid groups on the water-soluble polyacrylic acids (PAA) by the base consisting of zinc oxide or a mixture of zinc oxide and hydroxyapatite (HA). It was found that as the HA content of the cements increased, an increase in the dissolution behaviour of the cements occurred.

Original language	English (Ireland)
Pages (from-to)	347-352
Number of pages	6
Journal	Key Engineering Materials
Volume	218-220
Publication status	Published - 2002
Event	14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM) - Palm Springs, CA, United States Duration: 14 Nov 2001 → 17 Nov 2001

Cite this

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title = "In vitro response of osteoblast-like cells to hydroxyapatite-zinc oxide polyacrylic acid cements",

abstract = "The responses of an osteoblast-like cell line to hydroxyapatite-zinc oxide-polyalkonate cement composites were investigated. The experiments demonstrated that zinc-based cements were cytotoxic in vitro under certain conditions. The setting of these cements involved neutralisation of acid groups on the water-soluble polyacrylic acids (PAA) by the base consisting of zinc oxide or a mixture of zinc oxide and hydroxyapatite (HA). It was found that as the HA content of the cements increased, an increase in the dissolution behaviour of the cements occurred.",

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journal = "Key Engineering Materials",

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T1 - In vitro response of osteoblast-like cells to hydroxyapatite-zinc oxide polyacrylic acid cements

AU - Pembroke, J Tony

AU - Kenny, S.

AU - Buggy, M.

AU - Hill, R.

AU - Hatton, P. V.

PY - 2002

Y1 - 2002

N2 - The responses of an osteoblast-like cell line to hydroxyapatite-zinc oxide-polyalkonate cement composites were investigated. The experiments demonstrated that zinc-based cements were cytotoxic in vitro under certain conditions. The setting of these cements involved neutralisation of acid groups on the water-soluble polyacrylic acids (PAA) by the base consisting of zinc oxide or a mixture of zinc oxide and hydroxyapatite (HA). It was found that as the HA content of the cements increased, an increase in the dissolution behaviour of the cements occurred.

AB - The responses of an osteoblast-like cell line to hydroxyapatite-zinc oxide-polyalkonate cement composites were investigated. The experiments demonstrated that zinc-based cements were cytotoxic in vitro under certain conditions. The setting of these cements involved neutralisation of acid groups on the water-soluble polyacrylic acids (PAA) by the base consisting of zinc oxide or a mixture of zinc oxide and hydroxyapatite (HA). It was found that as the HA content of the cements increased, an increase in the dissolution behaviour of the cements occurred.

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M3 - Article

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SN - 1013-9826

VL - 218-220

SP - 347

EP - 352

JO - Key Engineering Materials

JF - Key Engineering Materials

T2 - 14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM)

Y2 - 14 November 2001 through 17 November 2001

ER -

In vitro response of osteoblast-like cells to hydroxyapatite-zinc oxide polyacrylic acid cements

Abstract

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