Interaction of bone proteins and cells with electrostatic domains on hydroxyapatite films

Marcela Salazar-Alvarez, Mohamed Radzi Noor, Tewfik Soulimane, Edmond Magner, Syed A.M. Tofail

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Protein adsorption is one of the first steps in the interactions with biomaterials' surface and they can also trigger adhesion of cells. This chapter discusses electrical modifications of hydroxyapatite (HA) and the creation of localized electrostatic charges on HA films to investigate biological interactions thereon. The nature of interactions of extracellular matrix proteins e.g. fibronectin and bone cells such as osteoblasts with such localised electrostatic domains has been discussed.

Original languageEnglish
Title of host publicationElectrically Active Materials for Medical Devices
PublisherImperial College Press
Pages405-416
Number of pages12
ISBN (Electronic)9781783269877
ISBN (Print)9781783269860
DOIs
Publication statusPublished - 1 Sep 2016

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