Abstract
This chapter presents an introduction to crystallization of organic fine chemicals and pharmaceutical compounds, written for newcomers to the field. The coverage includes the fundamental concepts of solubility, supersaturation, nucleation, growth, and polymorphism. We will also discuss the control of crystal size distribution, crystal shape and purity, and specifically address cooling crystallization and reaction crystallization processes.
Original language | English |
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Title of host publication | Molecules |
Subtitle of host publication | Nucleation, Aggregation and Crystallization: Beyond Medical and Other Implications |
Publisher | World Scientific Publishing Co. |
Pages | 145-172 |
Number of pages | 28 |
ISBN (Electronic) | 9789812832665 |
ISBN (Print) | 9812832645, 9789812832641 |
DOIs | |
Publication status | Published - 1 Jan 2009 |
Externally published | Yes |
Keywords
- Control
- Crystallization
- Growth
- Nucleation
- Polymorphism
- Purity
- Shape
- Size
- Solubility
- Supersaturation