Introduction to crystallization of fine chemicals and pharmaceuticals

Ake C. Rasmuson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This chapter presents an introduction to crystallization of organic fine chemicals and pharmaceutical compounds, written for newcomers to the field. The coverage includes the fundamental concepts of solubility, supersaturation, nucleation, growth, and polymorphism. We will also discuss the control of crystal size distribution, crystal shape and purity, and specifically address cooling crystallization and reaction crystallization processes.

Original languageEnglish
Title of host publicationMolecules
Subtitle of host publicationNucleation, Aggregation and Crystallization: Beyond Medical and Other Implications
PublisherWorld Scientific Publishing Co.
Pages145-172
Number of pages28
ISBN (Electronic)9789812832665
ISBN (Print)9812832645, 9789812832641
DOIs
Publication statusPublished - 1 Jan 2009
Externally publishedYes

Keywords

  • Control
  • Crystallization
  • Growth
  • Nucleation
  • Polymorphism
  • Purity
  • Shape
  • Size
  • Solubility
  • Supersaturation

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