TY - JOUR
T1 - Joint model for longitudinal mixture of normal and zero-inflated power series correlated responses Abbreviated title:mixture of normal and zero-inflated power series random-effects model
AU - Sharifian, Nastaran
AU - Bahrami Samani, Ehsan
AU - Ganjali, Mojtaba
N1 - Publisher Copyright:
© 2020 Taylor & Francis Group, LLC.
PY - 2021
Y1 - 2021
N2 - In this paper, a joint model is presented for analyzing longitudinal continuous and count mixed responses. The frequency distribution of continuous longitudinal response variable for each subject at any time has a skewed and or multi-modal form. Then, a suitable finite mixture of normals is used as its distribution. It seems that the continuous response comes from several distinct sub-populations. The number of zeros of the count response is inflated. Also, a zero-inflated power series (ZIPS) distribution is applied as its distribution in order to model the count response. The correlation of longitudinal responses through time and that of mixed continuous and count responses are modeled by utilizing the random-effects vectors in the finite mixtures of regression (FMR) models. Further, a full likelihood-based approach is used to obtain the maximum likelihood estimates of parameters via the EM algorithm. Then, some simulation studies are performed for assessing the performance of the model. Additionally, an application is illustrated for joint analysis of the number of days during the last month that the individual drank alcohol, as well as the respondents’ weight. Finally, the two first times of the Americans Changing Lives survey are evaluated.
AB - In this paper, a joint model is presented for analyzing longitudinal continuous and count mixed responses. The frequency distribution of continuous longitudinal response variable for each subject at any time has a skewed and or multi-modal form. Then, a suitable finite mixture of normals is used as its distribution. It seems that the continuous response comes from several distinct sub-populations. The number of zeros of the count response is inflated. Also, a zero-inflated power series (ZIPS) distribution is applied as its distribution in order to model the count response. The correlation of longitudinal responses through time and that of mixed continuous and count responses are modeled by utilizing the random-effects vectors in the finite mixtures of regression (FMR) models. Further, a full likelihood-based approach is used to obtain the maximum likelihood estimates of parameters via the EM algorithm. Then, some simulation studies are performed for assessing the performance of the model. Additionally, an application is illustrated for joint analysis of the number of days during the last month that the individual drank alcohol, as well as the respondents’ weight. Finally, the two first times of the Americans Changing Lives survey are evaluated.
KW - finite mixture distributions
KW - joint model
KW - longitudinal studies
KW - Mixed correlated responses
KW - random effect
KW - the EM algorithm
KW - the finite mixture of normals
KW - zero-inflated
UR - https://www.scopus.com/pages/publications/85090239242
U2 - 10.1080/10543406.2020.1814798
DO - 10.1080/10543406.2020.1814798
M3 - Article
C2 - 32881606
AN - SCOPUS:85090239242
SN - 1054-3406
VL - 31
SP - 117
EP - 140
JO - Journal of Biopharmaceutical Statistics
JF - Journal of Biopharmaceutical Statistics
IS - 2
ER -