Label free infrared nanoscopy: Impact on biology and medical devices

Susan M. Daly, Rabah Mouras, Christophe Silien, Syed A.M. Tofail

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This overview seeks to highlight those technologies which are poised at the forefront of functional, chemical and morphological imaging. Both labelled and label-free techniques are considered, with a particular emphasis on label-free, high resolution ambient imaging techniques. The analysis of the IR spectra of materials reveals a tell-tale 'fingerprint' of the molecule in terms of the absorption experienced in response to the vibrational frequency of bonds (functional groups) present. The novel employment of nonlinear (de-)excitation of materials in an effort to surpass the resolution limit imposed by diffraction is also addressed.

Original languageEnglish
Title of host publicationElectrically Active Materials for Medical Devices
PublisherImperial College Press
Pages451-471
Number of pages21
ISBN (Electronic)9781783269877
ISBN (Print)9781783269860
DOIs
Publication statusPublished - 1 Sep 2016

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