Mesenteric-based surgery for Crohn's disease: evidence and perspectives

Ming Duan, J. Calvin Coffey, Yi Li

Research output: Contribution to journalReview articlepeer-review

Abstract

Postoperative anastomotic recurrence of Crohn's disease is challenging and can lead to symptom recurrence and further surgery. The mesenteric pole of the intestine is the initial site of macroscopic anastomotic recurrence, and the mesentery may play an important role in recurrence after surgical resection. Therefore, “mesenteric-based surgery” has gained increasing attention by clinicians. However, the role of mesentery in the postoperative recurrence remains controversial. This review will examine mesenteric changes in Crohn's disease, proposed roles for mesentery in disease progression, and the potential for mesenteric-based surgery in the surgical management of Crohn disease.

Original languageEnglish
Pages (from-to)51-59
Number of pages9
JournalSurgery
Volume176
Issue number1
DOIs
Publication statusPublished - Jul 2024
Externally publishedYes

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