Metabolic Approaches to the Treatment of Autism Spectrum Disorders

Neluwa Liyanage R. Indika; Susan C. Owens; Udara D. Senarathne; Andreas M. Grabrucker; Nelson S.K. Lam; Kerri Louati; Greer McGuinness; Richard E. Frye

doi:10.1007/978-3-031-42383-3_14

Metabolic Approaches to the Treatment of Autism Spectrum Disorders

Neluwa Liyanage R. Indika, Susan C. Owens, Udara D. Senarathne, Andreas M. Grabrucker, Nelson S.K. Lam, Kerri Louati, Greer McGuinness, Richard E. Frye

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Children with autism spectrum disorder (ASD) may exhibit metabolic abnormalities, either with or without an underlying inherited metabolic disorder. Some of these metabolic abnormalities can be targeted by various metabolic therapies. For instance, supplementation with vitamins, minerals, and cofactors can offer therapeutic benefits to ASD associated with nutritional deficiencies resulting from factors such as reduced intake, genetic defects, autoantibodies disrupting vitamin transport, and the accumulation of harmful compounds depleting vitamins. Notably, some nutrients exhibit effects beyond their role as enzyme cofactors, and synergistic effects can be achieved through strategic combinations. This chapter outlines different metabolic therapies with their potential benefits in ASD.

Original language	English
Title of host publication	Neurobiology of Autism Spectrum Disorders
Publisher	Springer International Publishing
Pages	291-312
Number of pages	22
ISBN (Electronic)	9783031423833
ISBN (Print)	9783031423826
DOIs	https://doi.org/10.1007/978-3-031-42383-3_14
Publication status	Published - 1 Jan 2024

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Metabolic Approaches to the Treatment of Autism Spectrum Disorders

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