TY - JOUR
T1 - Metabolite differentiation and antiobesity effects between different grades of Yuexi Cuilan green tea
AU - Li, Ru
AU - Peng, Su
AU - Ye, Hong
AU - Li, Daxing
AU - Granato, Daniel
AU - Guo, Huimin
AU - Xie, Zhongwen
N1 - Publisher Copyright:
© 2021
PY - 2021/12
Y1 - 2021/12
N2 - The distinct chemical compounds and health benefits between different grades of YCGT have not been reported yet. The current study employed untargeted and targeted metabolomic approaches to analyze grade-related characteristic metabolites, and used high-fat diet (HFD) induced obese mice to evaluate antiobesity effects among four grades of Yuexi Cuilan green tea (YCGT). Based on chemical profiles and quantitative analysis, second premium grade (SP) exhibited a high similarity with first grade (FG), and proposed to be merged into FG. A total of 41 differentiated metabolites were screened and identified among four grades of YCGT. There were 18 chemical markers closely correlated with grades, mainly phenolic acids and carbohydrates. In addition, dietary supplementation of YCGT significantly decreased body weight and fat mass in HFD fed C57BL/6J mice, and the antiobesity effects were more profound for the FP grade than that of other lower grades.
AB - The distinct chemical compounds and health benefits between different grades of YCGT have not been reported yet. The current study employed untargeted and targeted metabolomic approaches to analyze grade-related characteristic metabolites, and used high-fat diet (HFD) induced obese mice to evaluate antiobesity effects among four grades of Yuexi Cuilan green tea (YCGT). Based on chemical profiles and quantitative analysis, second premium grade (SP) exhibited a high similarity with first grade (FG), and proposed to be merged into FG. A total of 41 differentiated metabolites were screened and identified among four grades of YCGT. There were 18 chemical markers closely correlated with grades, mainly phenolic acids and carbohydrates. In addition, dietary supplementation of YCGT significantly decreased body weight and fat mass in HFD fed C57BL/6J mice, and the antiobesity effects were more profound for the FP grade than that of other lower grades.
KW - Chemometrics analysis
KW - Grade evaluation
KW - Obesity
KW - UHPLC-Orbitrap-MS/MS
KW - Yuexi Cuilan green tea
UR - http://www.scopus.com/inward/record.url?scp=85116859659&partnerID=8YFLogxK
U2 - 10.1016/j.jff.2021.104794
DO - 10.1016/j.jff.2021.104794
M3 - Article
AN - SCOPUS:85116859659
SN - 1756-4646
VL - 87
JO - Journal of Functional Foods
JF - Journal of Functional Foods
M1 - 104794
ER -