Metabolite differentiation and antiobesity effects between different grades of Yuexi Cuilan green tea

Ru Li, Su Peng, Hong Ye, Daxing Li, Daniel Granato, Huimin Guo, Zhongwen Xie

Research output: Contribution to journalArticlepeer-review

Abstract

The distinct chemical compounds and health benefits between different grades of YCGT have not been reported yet. The current study employed untargeted and targeted metabolomic approaches to analyze grade-related characteristic metabolites, and used high-fat diet (HFD) induced obese mice to evaluate antiobesity effects among four grades of Yuexi Cuilan green tea (YCGT). Based on chemical profiles and quantitative analysis, second premium grade (SP) exhibited a high similarity with first grade (FG), and proposed to be merged into FG. A total of 41 differentiated metabolites were screened and identified among four grades of YCGT. There were 18 chemical markers closely correlated with grades, mainly phenolic acids and carbohydrates. In addition, dietary supplementation of YCGT significantly decreased body weight and fat mass in HFD fed C57BL/6J mice, and the antiobesity effects were more profound for the FP grade than that of other lower grades.

Original languageEnglish
Article number104794
JournalJournal of Functional Foods
Volume87
DOIs
Publication statusPublished - Dec 2021

Keywords

  • Chemometrics analysis
  • Grade evaluation
  • Obesity
  • UHPLC-Orbitrap-MS/MS
  • Yuexi Cuilan green tea

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